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indirubin

Known as: indigo red 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (3)

Antibiotics, AntineoplasticColoring AgentsIndoles

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Indirubin Inhibits LPS-Induced Inflammation via TLR4 Abrogation Mediated by the NF-kB and MAPK Signaling Pathways
Indirubin plays an important role in the treatment of many chronic diseases and exhibits strong anti-inflammatory activity… 
Highly Cited
2008
Highly Cited
2008
Dissection of mechanisms of Chinese medicinal formula Realgar-Indigo naturalis as an effective treatment for promyelocytic leukemia
To enhance therapeutic efficacy and reduce adverse effects, practitioners of traditional Chinese medicine (TCM) prescribe a… 
Highly Cited
2005
Highly Cited
2005
Indirubin derivatives inhibit Stat3 signaling and induce apoptosis in human cancer cells
Stat3 protein has an important role in oncogenesis and is a promising anticancer target. Indirubin, the active component of a… 
Highly Cited
2003
Highly Cited
2003
GSK-3-selective inhibitors derived from Tyrian purple indirubins.
Review
2002
Review
2002
Indirubin and Meisoindigo in the Treatment of Chronic Myelogenous Leukemia in China
The aim of this review is to summarize our experience and the current knowledge on the clinical results of Indirubin, a minor… 
Highly Cited
2001
Highly Cited
2001
Indirubin and Indigo Are Potent Aryl Hydrocarbon Receptor Ligands Present in Human Urine*
Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that regulates genes involved in xenobiotic metabolism… 
Highly Cited
2001
Highly Cited
2001
Indirubins inhibit glycogen synthase kinase-3 beta and CDK5/p25, two protein kinases involved in abnormal tau phosphorylation in Alzheimer's disease. A property common to most cyclin-dependent kinase…
The bis-indole indirubin is an active ingredient of Danggui Longhui Wan, a traditional Chinese medicine recipe used in the… 
Highly Cited
2001
Highly Cited
2001
Identification of an indigo precursor from leaves of Isatis tinctoria (Woad).
Highly Cited
2001
Highly Cited
2001
A P450 BM-3 mutant hydroxylates alkanes, cycloalkanes, arenes and heteroarenes.
Highly Cited
1999
Highly Cited
1999
Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases
Indirubin is the active ingredient of Danggui Longhui Wan, a mixture of plants that is used in traditional Chinese medicine to… 
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