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indacrinone

Known as: 6,7-dichloro-2-methyl-1-oxo-2-phenyl-5-indanyloxyacetic acid, indanone 
An orally active, indanone-based loop diuretic that consists of a racemic mixture. The (-) enantiomer is natriuretic, and the (+) enantiomer is… 
National Institutes of Health

Papers overview

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2013
2013
A novel multicatalytic MBH-Michael tandem reaction has been developed for the asymmetric assembly of ninhydrin, nitroolefins and… 
2009
2009
Indanocine, a synthetic indanone, has shown potential antiproliferative activity against several tumor types. It is different… 
2007
2007
A new facile approach toward natural and unnatural indanones has been developed, featuring a solid-supported [2+2+2… 
2004
2004
As part of an ongoing search for novel molecules with therapeutic potential we examined the mediator release inhibition activity… 
1994
1994
SummaryIn the preceding paper we reported on a docking study with the SYSDOC program for predicting the binding sites of… 
Highly Cited
1977
Highly Cited
1977
dl-Pumiliotoxin-C (4) was synthesized in a practical manner from trans-4-hexenal (9). The key step 14 15 (Scheme 3) involves an…