indacrinone

Known as: 6,7-dichloro-2-methyl-1-oxo-2-phenyl-5-indanyloxyacetic acid, indanone 
An orally active, indanone-based loop diuretic that consists of a racemic mixture. The (-) enantiomer is natriuretic, and the (+) enantiomer is… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1947-2018
051019472017

Papers overview

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2011
2011
Vimang is a standardized extract derived from Mango bark (Mangifera Indica L.), commonly used as anti-inflammatory phytomedicine… (More)
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Highly Cited
2007
Highly Cited
2007
Recent clinical studies reveal that selective agonists of group II metabotropic glutamate (mGlu) receptors have robust efficacy… (More)
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2007
2007
Group II metabotropic glutamate receptors (mGluRs), mGluR2 and mGluR3, play a number of important roles in mammalian brain and… (More)
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Highly Cited
2006
Highly Cited
2006
Previous studies indicate that agonists of the group II metabotropic glutamate receptors (mGluRs), mGluR2 and mGluR3, may provide… (More)
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2005
2005
A new series of donepezil-tacrine hybrid related derivatives have been synthesised as dual acetylcholinesterase inhibitors that… (More)
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2005
2005
We have identified and synthesized a series of phenyl-tetrazolyl and 4-thiopyridyl indanones as allosteric potentiators of the… (More)
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2000
2000
Most investigators would agree that the ideal chemotherapeutic agent should be 1) directed at a validated target; 2) potent… (More)
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1997
1997
Identification of new metabolites and demonstration of key enzyme activities support and extend the pathways previously reported… (More)
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1996
1996
The phase III drug-candidate, E2020, developed for treatment of Alzheimer's disease, and possibly other demenitas, and its… (More)
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1995
1995
Following the discovery of a new series of anti-acetylcholinesterase (anti-AChE) inhibitors such as 1-benzyl-4-[2-(N-benzoylamino… (More)
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