Indanones

Recent reports document that α-tetralone (3,4-dihydro-2H-naphthalen-1-one) is an appropriate scaffold for the design of high… (More)

In an attempt to discover a potent and selective anticancer agent, gallic acid has been modified to benzylidene indanones as… (More)

Novel 5-aryl indanones, inden-1-one oximes, and inden-1-ols were synthesized and evaluated as progesterone receptor (PR… (More)

We have identified and synthesized a series of biphenyl-carboxylic acid indanones as allosteric potentiators of the metabotropic… (More)

We have identified and synthesized a series of phenyl-tetrazolyl and 4-thiopyridyl indanones as allosteric potentiators of the… (More)

Sixty-four new indanones and thiaindanones related to donepezil were synthesized and evaluated in vitro as potential AChE… (More)

As part of an ongoing search for novel molecules with therapeutic potential we examined the mediator release inhibition activity… (More)

Identification of new metabolites and demonstration of key enzyme activities support and extend the pathways previously reported… (More)

The (E)-2-(4-pyridylmethylene)-1-indanones(E)-1-(E)-5[(E)-1,H;(E)-2,4- OCH3; (E)-3,5-OCH3; (E)-4,4-OH;(E)-5,5-OH] were obtained… (More)

CGP 28237 (5-methylsulphonylamino-6-phenoxy-1-indanone) belongs to a series of structurally novel indanones. The compound is a… (More)