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Bioactive diterpenes from Orthosiphon labiatus and Salvia africana-lutea.
TLDR
The known (+)-trans-ozic acid and two new labdane diterpenoids have been isolated from an ethanol extract of Orthosiphon labiatus and showed cytotoxic activity with IC50 82 and 69 microM, respectively, against a breast (MCF-7) human cancer cell line.
Analgesic, anti-inflammatory, antipyretic and haematological effects of aethiopinone, an o-naphthoquinone diterpenoid from Salvia aethiopis roots and two hemisynthetic derivatives.
TLDR
The compounds tested showed low toxicity and a pharmacological profile similar to other NSAI substances on reducing the edema induced by carrageenan and contractions induced by phenyl-p-quinone; the most active compounds were 1 and 2.
A complete 1H and 13C NMR data assignment for four drimane sesquiterpenoids isolated from Drimys winterii
From the bark of Drimys winterii Forst., the drimane derivatives drimendiol, polygodial, isotadeonal and isodrimeninol were isolated. Complete and unambiguous 1H and 13C NMR chemical shift
Antimycobacterial Metabolites from Plectranthus: Royleanone Derivatives against Mycobacterium tuberculosis Strains
TLDR
The antimycobacterial activities of eight diterpenes and eleven esters, 9–19, of 7α‐acetoxy‐6β, 12‐dihydroxyabieta‐8,12‐diene‐11,14‐dione and 9–14, 16, 18, and 19, as well as the NMR data of known derivatives 15 and 17 are reported.
Neoclerodane Diterpenoids from Scutellaria polyodon
Nine new neoclerodane diterpenoids, scupolins A−I, have been isolated from an Me2CO extract of the aerial parts of Scutellaria polyodon (3−11), together with the known neoclerodanes jodrellin B (1)
Effect of abietane diterpenes from Plectranthus grandidentatus on the growth of human cancer cell lines.
TLDR
Five known abietane diterpenes, fatty acid esters of 7alpha-acyloxy-6beta-hydroxyroyleanone, and coleon U, isolated from Plectranthus grandidentatus Gürke, were evaluated for their in vitro antiproliferative activity against five human cancer cell lines.
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