imidazolone
National Institutes of Health
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Advanced glycation end products (AGEs) are generated not only from glucose but also from several aldehydes such as methylglyoxal…
The nonenzymatic glycation of proteins by reducing sugars, also known as the Maillard reaction, has received increasing…
[reaction: see text] The solution and solid-phase synthesis of imidazolones is reported. The key step for the preparation of…
The cyclopentylpropylimidazolidinone L-766,892 is a potent beta3 AR agonist (EC50 5.7 nM, 64% activation) with 420- and 130-fold…
The modification of long-lived proteins with advanced glycation endproducts (AGEs) has been hypothesised to contribute to the…
A series of novel spirocyclic benzopyran imidazolones were synthesized as rigid analogues of cromakalim. These compounds cause a…