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hypericin

Known as: 1,3,4,6,8,13-hexahydroxy-10,11-dimethylphenanthro(1,10,9,8-opqra)perylene-7,14-dione, 4,5,7,4',5',7'-Hexahydroxy-2,2'-dimethyl-mesonapthtodianthron 
An anthraquinone derivative that is naturally found in the yellow flower of Hypericum perforatum (St. John's wort) with antidepressant, potential… 
National Institutes of Health

Related topics

Related topics

9 relations

Broader (7)

Antidepressive AgentsAntineoplastic AgentsAntiviral AgentsEnzyme Inhibitors
NCIt Antineoplastic Agent Terminologyanalogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2010
Review
2010
Hypericins as Potential Leads for New Therapeutics
70 years have passed since the first isolation of the naphthodianthrones hypericin and pseudohypericin from Hypericum perforatum… 
Highly Cited
2010
Highly Cited
2010
Investigations on the in vivo wound healing potential of Hypericum perforatum L.
Review
2006
Review
2006
MDR- and CYP3A4-mediated drug-herbal interactions.
Review
2005
Review
2005
Hypericin--the facts about a controversial agent.
Hypericin is a naturally occurring substance found in the common St. John's Wort (Hypericum species) and can also be synthesized… 
Review
2002
Review
2002
Hypericin in cancer treatment: more light on the way.
Review
2002
Review
2002
Hypericin--a new antiviral and antitumor photosensitizer: mechanism of action and interaction with biological macromolecules.
Hypericin, a naturally occurring pigment, is found in certain species of plants from the genus Hypericum, the most common of… 
Highly Cited
2000
Highly Cited
2000
An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures.
Highly Cited
1999
Highly Cited
1999
Palladium-catalyzed annulation
Abstract The palladium-catalyzed annulation of cyclic and bicyclic alkenes, unsaturated cyclopropanes and cyclobutanes, allenes… 
Highly Cited
1993
Highly Cited
1993
Photodynamic inactivation of infectivity of human immunodeficiency virus and other enveloped viruses using hypericin and rose bengal: inhibition of fusion and syncytia formation.
The mechanism of the antiviral activity of hypericin was characterized and compared with that of rose bengal. Both compounds… 
Highly Cited
1988
Highly Cited
1988
Therapeutic agents with dramatic antiretroviral activity and little toxicity at effective doses: aromatic polycyclic diones hypericin and pseudohypericin.
Two aromatic polycyclic diones hypericin and pseudohypericin have potent antiretroviral activity; these substances occur in… 
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