hydroxyitraconazole
National Institutes of Health
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Background A steady-state trough plasma itraconazole concentration greater than 500 ng/mL is a therapeutic target for…
To assess the drug interaction between oral solution itraconazole and calcineurin inhibitors, 10 recipients of allogeneic…
A rapid and sensitive liquid chromatography-isotope dilution tandem mass spectrometry method was developed and validated for…
This investigation was designed to evaluate the single-dose pharmacokinetics of itraconazole, hydroxyitraconazole, and…
This study examined the pharmacokinetic disposition, oral absorption and hepatic extraction of itraconazole and its active…
We studied seven healthy volunteers given itraconazole 200 mg orally or placebo, once daily for 4 days, in a crossover study. On…
The capacity of hydroxyitraconazole, an in-vivo metabolite of the antifungal agent itraconazole, to inhibit human cytochrome…