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A method for estimating the probability of adverse drug reactions
- C. Naranjo, U. Busto, D. Greenblatt
- MedicineClinical pharmacology and therapeutics
- 1 August 1981
TLDR
Evaluation of 3'-azido-3'-deoxythymidine, morphine, and codeine as probe substrates for UDP-glucuronosyltransferase 2B7 (UGT2B7) in human liver microsomes: specificity and influence of the UGT2B7*2…
- M. Court, S. Krishnaswamy, D. Greenblatt
- BiologyDrug metabolism and disposition: the biological…
- 1 September 2003
TLDR
Effects of the Antifungal Agents on Oxidative Drug Metabolism
- K. Venkatakrishnan, L. Moltke, D. Greenblatt
- Biology, MedicineClinical pharmacokinetics
- 1 February 2000
TLDR
CYP2B6 mediates the in vitro hydroxylation of bupropion: potential drug interactions with other antidepressants.
- L. Hesse, K. Venkatakrishnan, D. Greenblatt
- Biology, ChemistryDrug metabolism and disposition: the biological…
- 1 October 2000
TLDR
In vitro metabolism of midazolam, triazolam, nifedipine, and testosterone by human liver microsomes and recombinant cytochromes p450: role of cyp3a4 and cyp3a5.
- K. Patki, L. V. von Moltke, D. Greenblatt
- Biology, MedicineDrug metabolism and disposition: the biological…
- 1 July 2003
TLDR
Differentiation of intestinal and hepatic cytochrome P450 3A activity with use of midazolam as an in vivo probe: Effect of ketoconazole
- S. Tsunoda, R. Velez, L. Moltke, D. Greenblatt
- Biology, MedicineClinical pharmacology and therapeutics
- 1 November 1999
Human Drug Metabolism and the Cytochromes P450: Application and Relevance of In Vitro Models
- K. Venkatakrishnan, L. Moltke, D. Greenblatt
- Biology, ChemistryJournal of clinical pharmacology
- 1 November 2001
TLDR
Effect of Obesity on the Pharmacokinetics of Drugs in Humans
- M. Hanley, D. Abernethy, D. Greenblatt
- Medicine, BiologyClinical pharmacokinetics
- 2010
TLDR
Pharmacogenetic determinants of interindividual variability in bupropion hydroxylation by cytochrome P450 2B6 in human liver microsomes.
TLDR
Apparent mechanism-based inhibition of human CYP2D6 in vitro by paroxetine: comparison with fluoxetine and quinidine.
- K. Bertelsen, K. Venkatakrishnan, L. V. von Moltke, R. Obach, D. Greenblatt
- Biology, ChemistryDrug metabolism and disposition: the biological…
- 1 March 2003
TLDR
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