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hydroxyflutamide

Known as: alpha, alpha, alpha-trifluoro-2-methyl-4'-nitro-m-lactotoluidide, 2-Hydroxy-2-methyl-N-(4-nitro-3-(trifluoromethyl)phenyl)propanamide, 2-Hydroxyflutamide 
National Institutes of Health

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5 relations

Narrower (2)

2-hydroxyflutamideSch 16423

Broader (2)

Androgen AntagonistsFlutamide
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Suppression of androgen receptor enhances the self-renewal of mesenchymal stem cells through elevated expression of EGFR.
2006
2006
Ligands with a 3,3-diphenylpentane skeleton for nuclear vitamin D and androgen receptors: Dual activities and metabolic activation.
2006
2006
Chiral dimethylamine flutamide derivatives--modeling, synthesis, androgen receptor affinities and carbon-11 labeling.
2005
2005
A new class of androgen receptor antagonists bearing carborane in place of a steroidal skeleton.
Review
2004
Review
2004
Expression and function of androgen receptor coactivators in prostate cancer
2003
2003
Evidence that dehydroepiandrosterone, DHEA, directly inhibits GnRH gene expression in GT1–7 hypothalamic neurons
Highly Cited
1999
Highly Cited
1999
The Anti‐Androgen Hydroxyflutamide and Androgens Inhibit Interleukin‐6 Production by an Androgen‐Responsive Human Osteoblastic Cell Line
While androgens clearly have significant skeletal effects, the paracrine mediators of androgen action on bone are at present… 
Highly Cited
1995
Highly Cited
1995
Effects of short-term exposure to hydroxyflutamide in utero on the development of the reproductive tract in male mice.
To determine if and when short-term ablation of androgen action compromises the development of the male reproductive tract in… 
Highly Cited
1991
Highly Cited
1991
Androgen sensitivity of the new human breast cancer cell line MFM-223.
The mammary carcinoma cell line MFM-223 is characterized by high androgen and low estrogen and progesterone receptor levels. With… 
Highly Cited
1987
Highly Cited
1987
Testosterone inhibits cAMP-induced de Novo synthesis of Leydig cell cytochrome P-450(17 alpha) by an androgen receptor-mediated mechanism.
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