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histone deacetylase activity

Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction represents the removal of an acetyl group… 
National Institutes of Health

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Histone Deacetylasehistone deacetylase inhibitor activity

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Histone Deacetylation

Papers overview

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2009
2009
Effects of calorie restriction on mesenchymal stem cells
INTRODUCTION: Calorie restriction (CR) is the most effective way known to extend the lifespan of various organisms including… 
2007
2007
Small Molecule Targeting of G Reduces -Adrenergic Receptor Desensitization and Normalizes Cardiac Dysfunction in an Acute Heart Failure Model
4th Annual Symposium of the American Heart Association Council on Basic Cardiovascular Sciences Cardiovascular Repair and… 
2004
2004
Pivanex inhibits histone deacetylase activity in non small cell lung cancer patients
4016 Pivanex™ (pivaloyloxymethyl butyrate) is a histone deacetylase (HDAC) inhibitor that distributes rapidly into tissues and… 
2003
2003
Functional interplay between modulation of histone deacetylase activity and regulation of its biological roles, in the mitotic response
2000
2000
Receptor Unique Anti-Activator Protein-1 Activity of Retinoic Acid Updated Version
The anticancer effects of retinoids are mainly mediated by two classes of nuclear receptors, the retinoic acid receptors (RARs… 
2000
2000
Breast Cancer Cells by Histone Deacetylase Inhibition in Human α Transcriptional Activation of Estrogen Receptor Updated
Recent findings have established a connection between DNA methylation and transcriptionally inactive chromatin characterized by…