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histone acetyltransferase

Known as: Acetylase, Histone, Acetyltransferases, Histone, histone acetyltransferases (HAT) 
Class of enzymes that catalyze the acetylation of specific lysine residues of histones, proteins that organize eukaryotic DNA into chromatin. Among… 
National Institutes of Health

Related topics

Related topics

34 relations
ATF2 protein, humanEnzyme GeneHistone AcetylationIn Blood

Narrower (17)

EP300 protein, humanElp3 protein, S pombeEnok protein, DrosophilaGCN5 histone acetyltransferase, mouse

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2005
Review
2005
Histone acetylation and deacetylation: importance in inflammatory lung diseases
Inflammatory lung diseases are characterised by increased expression of multiple inflammatory genes that are regulated by… 
Highly Cited
2003
Highly Cited
2003
Small Molecule Modulators of Histone Acetyltransferase p300*
Histone acetyltransferases (HATs) are a group of enzymes that play a significant role in the regulation of gene expression. These… 
Highly Cited
2001
Highly Cited
2001
Snf1--a Histone Kinase That Works in Concert with the Histone Acetyltransferase Gcn5 to Regulate Transcription
Modification of histones is an important element in the regulation of gene expression. Previous work suggested a link between… 
Highly Cited
2001
Highly Cited
2001
Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases.
Highly Cited
2000
Highly Cited
2000
The structural basis for the recognition of acetylated histone H4 by the bromodomain of histone acetyltransferase Gcn5p
The bromodomain is an ∼110 amino acid module found in histone acetyltransferases and the ATPase component of certain nucleosome… 
Highly Cited
1999
Highly Cited
1999
Esa1p Is an Essential Histone Acetyltransferase Required for Cell Cycle Progression
ABSTRACT Histones are dynamically modified during chromatin assembly, as specific transcriptional patterns are established, and… 
Review
1999
Review
1999
Coactivator and corepressor complexes in nuclear receptor function.
Highly Cited
1998
Highly Cited
1998
Transcription factor-specific requirements for coactivators and their acetyltransferase functions.
Different classes of mammalian transcription factors-nuclear receptors, cyclic adenosine 3',5'-monophosphate-regulated enhancer… 
Highly Cited
1997
Highly Cited
1997
Steroid receptor coactivator-1 is a histone acetyltransferase
Steroid receptors and coactivator proteins are thought to stimulate gene expression by facilitating the assembly of basal… 
Highly Cited
1995
Highly Cited
1995
Identification of a Gene Encoding a Yeast Histone H4 Acetyltransferase (*)
A collection of yeast temperature-sensitive mutants was screened by an enzymatic assay to find a mutant defective in the… 
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