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Histone Acetylation

Histone Acetylation involves covalent linkage of acetyl groups to highly basic histone proteins associated with DNA, particularly in active chromatin… 
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Innovative epigenetic therapeutics comprise histone deacetylase inhibitors (HDAC‐I) and demethylating agents (DA). It was… 
Highly Cited
2005
Highly Cited
2005
ABSTRACT Several models have been proposed for the mechanism of chromatin remodelling across the promoters of inducible genes in… 
Highly Cited
2004
Highly Cited
2004
DNA methyltransferase 1 (DNMT1) catalyzes the post-replication methylation of DNA and is responsible for maintaining the DNA… 
Highly Cited
2000
Highly Cited
2000
Overexpression of c-Myc can lead to altered transcriptional regulation of cellular genes and to neoplastic transformation… 
Highly Cited
2000
Highly Cited
2000
The importance of control of the levels of histone acetylation for the control of gene expression in eukaryotic chromatin is… 
Highly Cited
1998
Highly Cited
1998
ABSTRACT In chromosome translocations characteristic of Burkitt lymphomas (BL) and murine plasmacytomas, c-myc genes become… 
Highly Cited
1985
Highly Cited
1985
Macro- and micronuclei of the ciliated protozoan, Tetrahymena thermophila, afford a unique opportunity to study histone… 
Highly Cited
1968
Highly Cited
1968
de-livered to stainless-steel planchets for drying and weighing and to 15 ml of Bray's scin- tillation mixture29 for measurement…