Histone Acetylation

Histone Acetylation involves covalent linkage of acetyl groups to highly basic histone proteins associated with DNA, particularly in active chromatin… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1966-2018
010020030019662018

Papers overview

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Highly Cited
2010
Highly Cited
2010
As the human life span increases, the number of people suffering from cognitive decline is rising dramatically. The mechanisms… (More)
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Highly Cited
2009
Highly Cited
2009
Histone acetylation in single-cell eukaryotes relies on acetyl coenzyme A (acetyl-CoA) synthetase enzymes that use acetate to… (More)
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Highly Cited
2009
Highly Cited
2009
The pleiotropic lipid mediator sphingosine-1-phosphate (S1P) can act intracellularly independently of its cell surface receptors… (More)
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Highly Cited
2004
Highly Cited
2004
Formation of long term memory begins with the activation of many disparate signaling pathways that ultimately impinge on the… (More)
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Highly Cited
2004
Highly Cited
2004
We studied a mouse model of the haploinsufficiency form of Rubinstein-Taybi syndrome (RTS), an inheritable disorder caused by… (More)
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Highly Cited
2004
Highly Cited
2004
Here we report that increased pup licking and grooming (LG) and arched-back nursing (ABN) by rat mothers altered the offspring… (More)
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Highly Cited
2003
Highly Cited
2003
In the mouse circadian clock, a transcriptional feedback loop is at the centre of the clockwork mechanism. Clock and Bmal1 are… (More)
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Highly Cited
2002
Highly Cited
2002
Naïve T cells differentiate into effector cells upon stimulation with antigen, a process that is accompanied by changes in the… (More)
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Highly Cited
2000
Highly Cited
2000
Histone deacetylases (HDACs) catalyze the removal of acetyl groups on the amino-terminal lysine residues of core nucleosomal… (More)
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Highly Cited
1996
Highly Cited
1996
We report the cloning of a transcription-associated histone acetyltransferase type A(HAT A). This Tetrahymena enzyme is… (More)
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