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Histone Acetylation

Histone Acetylation involves covalent linkage of acetyl groups to highly basic histone proteins associated with DNA, particularly in active chromatin… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Age-Old Problem With the increase in human life span, there is an associated increase in incidence of age-associated cognitive… Expand
Highly Cited
2009
Highly Cited
2009
Chromatin Modifier Modulates Gene Expression Modification of chromatin structure is usually thought of as a global, relatively… Expand
Review
2007
Review
2007
Histone acetylation regulates many cellular processes, and specific acetylation marks, either singly or in combination, produce… Expand
Highly Cited
2004
Highly Cited
2004
Formation of long term memory begins with the activation of many disparate signaling pathways that ultimately impinge on the… Expand
Highly Cited
2003
Highly Cited
2003
In the mouse circadian clock, a transcriptional feedback loop is at the centre of the clockwork mechanism. Clock and Bmal1 are… Expand
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Review
2002
Review
2002
The organization of eukaryotic chromatin has a major impact on all nuclear processes involving DNA substrates. Gene expression is… Expand
Highly Cited
2000
Highly Cited
2000
Histone deacetylases (HDACs) catalyze the removal of acetyl groups on the amino-terminal lysine residues of core nucleosomal… Expand
Review
1998
Review
1998
  • K. Struhl
  • Genes & development
  • 1998
  • Corpus ID: 13640082
More than 30 years ago, Vincent Allfrey proposed that histone acetylation was associated with transcriptional activity in… Expand
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Highly Cited
1996
Highly Cited
1996
We report the cloning of a transcription-associated histone acetyltransferase type A(HAT A). This Tetrahymena enzyme is… Expand
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Highly Cited
1988
Highly Cited
1988
An antiserum raised against chemically acetylated histone H4 was found to recognize the epitope epsilon‐N‐acetyl lysine. Affinity… Expand