herboxidiene

Known as: 2H-Pyran-2-acetic acid, tetrahydro-6-(6-(3-(3-hydroxy-2-methoxy-1-methylbutyl)-2-methyloxiranyl)-1,5-dimethyl-1,3-hexadienyl)-5-methyl-, GEX 1A, GEX1A compound 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2018
024619922018

Papers overview

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2017
2017
Constitutive and alternative splicing of pre-mRNAs from multiexonic genes controls the diversity of the proteome; these precisely… (More)
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2014
2014
Herboxidiene is a natural product that has previously been shown to exhibit antitumor activity by targeting the spliceosome. This… (More)
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2013
2013
The herboxidiene biosynthetic gene cluster contains a regulatory gene and six biosynthetic genes that encode three polyketide… (More)
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2012
2012
The 53-kb biosynthetic gene cluster for the novel anticholesterol natural product herboxidiene was identified in Streptomyces… (More)
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2007
2007
A convergent enantioselective synthesis of herboxidiene/GEX 1A (1) is described that features a double stereodifferentiating… (More)
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2002
2002
Six GEX1 compounds, GEX1A/herboxidiene and its related 5 novel compounds, were isolated from a culture broth of Streptomyces sp… (More)
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2002
2002
Six structurally related antitumor antibiotics named GEX1 compounds were isolated from a culture broth of Streptomyces sp. GEX1A… (More)
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2000
2000
The syntheses of simplified aromatic hybrids of the novel polyketide herboxidiene (1) are described. One of the hybrids prepared… (More)
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1997
1997
An abnormally elevated level of plasma cholesterol is one of the risk factors for the development of coronary heart disease… (More)
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1992
1992
Screening of microbial fermentation broths for herbicidal activity led to the discovery of a novel polyketide, herboxidiene, from… (More)
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