M. Banwell

Publications560
h-index33
Citations5,114
Highly Influential Citations21
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Use of Sulfated Linked Cyclitols as Heparan Sulfate Mimetics to Probe the Heparin/Heparan Sulfate Binding Specificity of Proteins*
Heparin and heparan sulfate (HS) are structurally diverse glycosaminoglycans (GAG) that are known to interact, via unique structural motifs, with a wide range of functionally distinct proteins and… Expand
Anti-Herpes Simplex Virus Activities of Two Novel Disulphated Cyclitols
By screening a library of sulphated compounds of low molecular weight, we have found that several cyclitol derivatives, each modified with two sulphate groups in addition to pyrrole and various… Expand
Antimicrobial and Cytotoxic Activities of Synthetically Derived Tambjamines C and E – J, BE‐18591, and a Related Alkaloid from the Marine Bacterium Pseudoalteromonas tunicata
In the first comprehensive biological assessment of the tambjamine class of marine alkaloids, synthetically derived samples of compounds 1–9 have been subjected to evaluation as antimicrobial agents… Expand
Analogues of SB-203207 as inhibitors of tRNA synthetases.
SB-203207 and 10 analogues have been prepared, by elaboration of altemicidin, and evaluated as inhibitors of isoleucyl, leucyl and valyl tRNA synthetases (IRS, LRS, and VRS, respectively).… Expand
Synthesis of NTA3-DTDA — A Chelator-Lipid that Promotes Stable Binding of His-Tagged Proteins to Membranes
A six-step reaction sequence is described for the preparation of compound 1 (NTA3-DTDA), a membrane-penetrating and potent chelator that can be incorporated into liposomes and plasma membrane… Expand
An enantioselective total synthesis of the stilbenolignan (−)-aiphanol and the determination of its absolute stereochemistry
Abstract The title natural product (−)-aiphanol has been prepared by total synthesis. A key step involved the asymmetric dihydroxylation of ( E )-3,5-dimethoxy-4-(methoxymethoxy)cinnamyl alcohol with… Expand
Rapid and convergent assembly of the polycyclic framework assigned to the cytotoxic marine alkaloid halitulin
Compound 3, representing the tetra-O-methyl ether derivative of structure, 1, assigned to the cytotoxic marine alkaloid halitulin, has been assembled in a convergent manner from the readily available… Expand
Biomimetic Preparation of the Racemic Modifications of the Stilbenolignan Aiphanol and Three Congeners
A chromatographically separable mixture of the racemic modification, (±)-1, of the stilbenolignan (–)-aiphanol and congeners (±)-2–4 has been generated by a silver(I)-mediated and potentially… Expand
Assessment of Double-Barrelled Heck Cyclizations as a Means for Construction of the 14-Phenyl-8,9-dihydro- 6H-[1]benzopyrano[4′,3′:4,5]pyrrolo[2,1-a]isoquinolin- 6-one Core Associated with Certain…
The 1,2,4-trisubstituted pyrrole (4), which is readily prepared from pyrrole itself, undergoes double- barrelled Heck cyclizations to give, inter alia, compounds (3) and (17) for which crystal… Expand
Whole-Cell Biotransformation of m-Ethyltoluene into 1S,6R-5-Ethyl-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylic Acid as an Approach to the C-Ring of the Binary Indole–Indoline Alkaloid Vinblastine
The title compound 3, a potential building block for the construction of analogues of the clinically important anti-cancer agent vinblastine (1), has been prepared in an efficient manner through a… Expand
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