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halofantrine

Known as: Halofantrina, Halofantrinum, halofantrine [Chemical/Ingredient] 
National Institutes of Health

Related topics

Related topics

14 relations

Broader (2)

AntimalarialsPhenanthrenes
Drug AllergyMalariaMalaria, FalciparumMalaria, Vivax

Narrower (3)

HalfanHalofantrine hydrochlorideWR 171,699

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Supersaturated Self-Nanoemulsifying Drug Delivery Systems (super-SNEDDS)
Highly Cited
2006
Highly Cited
2006
Decreasing pfmdr1 copy number in plasmodium falciparum malaria heightens susceptibility to mefloquine, lumefantrine, halofantrine, quinine, and artemisinin.
The global dissemination of drug-resistant Plasmodium falciparum is spurring intense efforts to implement artemisinin (ART)-based… 
Highly Cited
2004
Highly Cited
2004
Evidence for a central role for PfCRT in conferring Plasmodium falciparum resistance to diverse antimalarial agents.
Review
2002
Review
2002
Lipid-based formulations for intestinal lymphatic delivery.
Review
2001
Review
2001
Intestinal lymphatic drug transport: an update.
Highly Cited
2000
Highly Cited
2000
Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum
Throughout the latter half of this century, the development and spread of resistance to most front-line antimalarial compounds… 
Highly Cited
2000
Highly Cited
2000
Effect of short-, medium-, and long-chain fatty acid-based vehicles on the absolute oral bioavailability and intestinal lymphatic transport of halofantrine and assessment of mass balance in lymph…
The contribution of lymphatic transport and absorption directly into the portal blood to the overall oral bioavailability of a… 
Highly Cited
2000
Highly Cited
2000
The tyrosine-86 allele of the pfmdr1 gene of Plasmodium falciparum is associated with increased sensitivity to the anti-malarials mefloquine and artemisinin.
Highly Cited
2000
Highly Cited
2000
Plasmodium falciparum antimalarial drug susceptibility on the north-western border of Thailand during five years of extensive use of artesunate-mefloquine.
Review
1994
Review
1994
Epidemiology of drug resistance in malaria.
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