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Halofantrine hydrochloride

Known as: 1-(1,3-dichloro-6-trifluoromethyl-9-phenanthryl)-3-di(n-butyl)aminopropanol HCl 
National Institutes of Health

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Related topics

12 relations
AntimalarialsDrug AllergyMalariaMalaria, Falciparum

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HalfanWR 171,699

Broader (1)

halofantrine

Papers overview

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2004
2004
Pharmacokinetics of halofantrine and n-desbutylhalofantrine in patients with falciparum malaria following a multiple dose regimen of halofantrine
SummaryHalofantrine is a new blood schizontocidal drug used for the treatment of multidrug-resistant falciparum malaria. The… 
2001
2001
Stereoselective halofantrine disposition and effect: concentration-related QTc prolongation.
AIMS 1) To characterize the variability of multiple-dose halofantrine pharmacokinetics over time in healthy adults, 2) to… 
1994
1994
Clinical efficacy and pharmacokinetics of micronized halofantrine for the treatment of acute uncomplicated falciparum malaria in nonimmune patients.
Twenty-eight nonimmune patients with acute uncomplicated falciparum malaria returning from subSaharan Africa were treated with a… 
1993
1993
Pharmacokinetics, efficacy and toxicity of parenteral halofantrine in uncomplicated malaria.
1 The pharmacokinetics, efficacy and toxicity of a new parenteral formulation of halofantrine hydrochloride were evaluated in 12… 
1992
1992
Measurement of halofantrine and its major metabolite desbutylhalofantrine in plasma and blood by high-performance liquid chromatography: a new methodology.
1991
1991
Halofantrine hydrochloride--efficacy and safety in children with acute malaria.
Thirty two children with symptomatic malaria due to P. vivax and P. Falciparum infections were treated with three doses of… 
1990
1990
Clinical experience with halofantrine in the treatment of malaria.
Halofantrine hydrochloride (HF) belongs to a new class of antimalarials, the phenanthrene methanols. Preliminary clinical studies… 
Review
1989
Review
1989
Halofantrine: an overview of efficacy and safety
1989
1989
Structure of the antimalarial halofantrine hydrochloride.
1,3-Dichloro-alpha-[2-(dibutylamino)ethyl]-6-(trifluoromethyl)-9- phenanthrenemethanol hydrochloride, C26H31Cl2F3NO+.Cl-, Mr… 
1988
1988
CLINICAL TRIALS WITH HALOFANTRINE HYDROCHLORIDE IN MALAWI
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