growth hormone releasing hexapeptide

Known as: L-Lysinamide, L-histidyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-, (D-Trp(2)-D-Phe(5))GHRP, GHRP-6 
 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Oligopeptides

Narrower (1)

SK&F 110679

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
How does growth hormone releasing hexapeptide self-assemble in nanotubes?
Growth hormone releasing peptide, GHRP-6, a hexapeptide (His-(D-Trp)-Ala-Trp-(D-Phe)-Lys-NH2, MW = 872.44 Da) that belongs to a… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
2003
2003
Comparison of the prokinetic effects of ghrelin, GHRP-6 and motilin in rats in vivo and in vitro
 
Is this relevant?
Review
1999
Review
1999
Growth hormone in obesity
Growth hormone (GH) secretion, either spontaneous or evoked by provocative stimuli, is markedly blunted in obesity. In fact obese… (More)
  • figure 1
  • table 1
  • figure 2
  • table 2
Is this relevant?
1998
1998
Human fetal pituitary expresses functional growth hormone-releasing peptide receptors.
The synthetic hexapeptide GH-releasing peptide (GHRP) stimulates a dose-dependent release of GH in humans in vivo and in animals… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 3
  • figure 5
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Hypothalamic growth hormone secretagogue-receptor (GHS-R) expression is regulated by growth hormone in the rat.
Synthetic GH secretagogues (GHSs) act via a receptor (GHS-R) distinct from that for GH-releasing hormone (GHRH). We have studied… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Molecular analysis of rat pituitary and hypothalamic growth hormone secretagogue receptors.
GH release is thought to occur under the reciprocal regulation of two hypothalamic peptides, GH releasing hormone (GHRH) and… (More)
  • figure 2
  • figure 3
  • figure 4
  • figure 5
  • figure 7
Is this relevant?
Review
1997
Review
1997
Growth hormone-releasing peptides.
Growth hormone-releasing peptides (GHRPs) are synthetic, non-natural peptides endowed with potent stimulatory effects on… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 6
Is this relevant?
1994
1994
Growth hormone-releasing hexapeptide elevates intracellular calcium in rat somatotropes by two mechanisms.
The actions of GH-releasing hexapeptide (His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 or GHRP-6) on single rat somatotropes were studied using… (More)
Is this relevant?
1994
1994
Growth Hormone-Releasing Hexapeptide Is a Potent Stimulator of Growth Hormone Gene Expression and Release in the Growth Hormone—Releasing Hormone—Deprived Infant Rat
ABSTRACT: The growth hormone-releasing hexapeptide (GHRP-6) specifically stimulates growth hormone (GH) secretion in several… (More)
  • figure 1
  • figure 3
  • figure 2
  • figure 4
Is this relevant?
1993
1993
Massive growth hormone (GH) discharge in obese subjects after the combined administration of GH-releasing hormone and GHRP-6: evidence for a marked somatotroph secretory capability in obesity.
GH secretion in response to all provocative stimuli is decreased in patients with obesity. However, the precise mechanism causing… (More)
Is this relevant?