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growth hormone releasing hexapeptide

Known as: L-Lysinamide, L-histidyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-, (D-Trp(2)-D-Phe(5))GHRP, GHRP-6 
 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Oligopeptides

Narrower (1)

SK&F 110679

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2001
Review
2001
Unnatural growth hormone-releasing peptide begets natural ghrelin.
  • C. Bowers
  • The Journal of clinical endocrinology and…
  • 2001
    • Corpus ID: 31391775
Unnatural GH-releasing peptide (GHRP) finally has evolved into the highly probable natural GHRP designated ghrelin. The beginning… Expand
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Highly Cited
2000
Highly Cited
2000
Systemic Administration of Ghrelin Induces Fos and Egr‐1 Proteins in the Hypothalamic Arcuate Nucleus of Fasted and Fed Rats
Ghrelin, a recently identified endogenous ligand for the growth hormone secretagogue (GHS) receptor, induces growth hormone (GH… Expand
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Review
1999
Review
1999
Growth hormone in obesity
Growth hormone (GH) secretion, either spontaneous or evoked by provocative stimuli, is markedly blunted in obesity. In fact obese… Expand
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Highly Cited
1997
Highly Cited
1997
Molecular analysis of rat pituitary and hypothalamic growth hormone secretagogue receptors.
GH release is thought to occur under the reciprocal regulation of two hypothalamic peptides, GH releasing hormone (GHRH) and… Expand
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Highly Cited
1997
Highly Cited
1997
Hypothalamic growth hormone secretagogue-receptor (GHS-R) expression is regulated by growth hormone in the rat.
Synthetic GH secretagogues (GHSs) act via a receptor (GHS-R) distinct from that for GH-releasing hormone (GHRH). We have studied… Expand
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Highly Cited
1995
Highly Cited
1995
Central actions of peptide and non-peptide growth hormone secretagogues in the rat.
Evidence for a central site of action of growth-hormone-releasing peptide (GHRP-6) was sought by (1) counting the number of Fos… Expand
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Highly Cited
1993
Highly Cited
1993
A nonpeptidyl growth hormone secretagogue.
A nonpeptidyl secretagogue for growth hormone of the structure 3-amino-3-methyl-N-(2,3,4,5-tetrahydro-2-oxo-1-([2'-(1H-tetrazol-5… Expand
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Highly Cited
1993
Highly Cited
1993
Massive growth hormone (GH) discharge in obese subjects after the combined administration of GH-releasing hormone and GHRP-6: evidence for a marked somatotroph secretory capability in obesity.
GH secretion in response to all provocative stimuli is decreased in patients with obesity. However, the precise mechanism causing… Expand
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Highly Cited
1993
Highly Cited
1993
Effect of growth hormone (GH)-releasing hormone (GHRH), atropine, pyridostigmine, or hypoglycemia on GHRP-6-induced GH secretion in man.
His-DTrp-Ala-Trp-DPhe-Lys-NH2 (GHRP-6) is a synthetic compound that releases GH in a dose-related and specific manner in several… Expand
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Highly Cited
1989
Highly Cited
1989
The synergistic effects of His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 on growth hormone (GH)-releasing factor-stimulated GH release and intracellular adenosine 3',5'-monophosphate accumulation in rat primary…
His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 (GHRP-6) stimulated GH release from rat primary pituitary cells in a time- and dose-dependent… Expand
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