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Certain bacteria synthesize glutathionylspermidine (Gsp), from GSH and spermidine. Escherichia coli Gsp synthetase/amidase (GspSA… Expand Three possible methods for the facile synthesis of functionalized phosphinates, including the core of complex phosphinopeptide… Expand Glutathionylspermidine (Gsp) is a metabolite common to Escherichia coli and protozoal parasites of the Trypanosoma family. Though… Expand Glutathionylspermidine (GSP) synthetases of Trypanosomatidae and Escherichia coli couple hydrolysis of ATP (to ADP and Pi) with… Expand Intracellular levels of glutathione and glutathionylspermidine conjugates have been measured throughout the growth phases of… Expand Two enzymes involved in the biosynthesis of the trypanosomatid‐specific dithiol trypanothione‐glutathionylspermidine (Gsp… Expand Levels of the polyamines spermidine and putrescine and the major intracellular thiols glutathione (GSH), glutathionylspermidine… Expand The effect of D,L-alpha-difluoromethylornithine (DFMO) on thiol and polyamine levels in Trypanosoma brucei was investigated by… Expand Studies on the biosynthesis of trypanothione [N1,N8-bis(glutathionyl)-spermidine] in the insect trypanosomatid Crithidia… Expand Most of the spermidine in Escherichia coli is converted to glutathionylspermidine at the end of logarithmic growth. Methods are… Expand