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spermidine
Known as:
4-Azaoctamethylenediamine
, 1,4-Diaminobutane, N-(3-Aminopropyl)-
, 4-Azaoctane-1,8-Diamine
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A polyamine formed from putrescine. It is found in almost all tissues in association with nucleic acids. It is found as a cation at all pH values…
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National Institutes of Health
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Related topics
Related topics
50 relations
Narrower (40)
1-amino-8-acetamido-5-azanonane
1-methylspermidine
5,8-dimethylspermidine
6,6-difluorospermidine
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In Blood
agonists
analogs & derivatives
antagonists & inhibitors
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Broader (2)
Polyamines
Putrescine
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Spermidine in health and disease
F. Madeo
,
T. Eisenberg
,
F. Pietrocola
,
G. Kroemer
Science
2018
Corpus ID: 206659415
Having your longevity and eating too Although caloric restriction has clear benefits for maximizing health span and life span, it…
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Highly Cited
2016
Highly Cited
2016
Cardioprotection and lifespan extension by the natural polyamine spermidine
T. Eisenberg
,
M. Abdellatif
,
+56 authors
F. Madeo
Nature Medicine
2016
Corpus ID: 3985786
Aging is associated with an increased risk of cardiovascular disease and death. Here we show that oral supplementation of the…
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Review
2011
Review
2011
Autophagy and Aging
D. Rubinsztein
,
G. Mariño
,
G. Kroemer
Cell
2011
Corpus ID: 11610404
Highly Cited
2009
Highly Cited
2009
Induction of autophagy by spermidine promotes longevity
T. Eisenberg
,
H. Knauer
,
+26 authors
F. Madeo
Nature Cell Biology
2009
Corpus ID: 3126330
Ageing results from complex genetically and epigenetically programmed processes that are elicited in part by noxious or stressful…
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Highly Cited
2000
Highly Cited
2000
Oxidative stress and some antioxidant systems in acid rain-treated bean plants Protective role of exogenous polyamines
V. Velikova
,
I. Yordanov
,
A. Edreva
2000
Corpus ID: 56432274
Highly Cited
1997
Highly Cited
1997
Stretching DNA with optical tweezers.
M. Wang
,
H. Yin
,
R. Landick
,
J. Gelles
,
S. Block
Biophysical journal
1997
Corpus ID: 28626203
Highly Cited
1985
Highly Cited
1985
Trypanothione: a novel bis(glutathionyl)spermidine cofactor for glutathione reductase in trypanosomatids.
A. Fairlamb
,
P. Blackburn
,
P. Ulrich
,
B. Chait
,
A. Cerami
Science
1985
Corpus ID: 22800459
Glutathione reductase from trypanosomes and leishmanias, unlike glutathione reductase from other organisms, requires an unusual…
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Highly Cited
1983
Highly Cited
1983
The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme
C. Guerrier-Takada
,
K. Gardiner
,
T. Marsh
,
N. Pace
,
S. Altman
Cell
1983
Corpus ID: 39111511
Review
1976
Review
1976
1,4-Diaminobutane (putrescine), spermidine, and spermine.
C. Tabor
,
H. Tabor
Annual review of biochemistry
1976
Corpus ID: 9539758
As is evident from the above summary of the recent literature, plus many other papers not cited here, there is an extensive…
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Highly Cited
1960
Highly Cited
1960
The role of polyamines in the neutralization of bacteriophage deoxyribonucleic acid.
B. Ames
,
D. Dubin
The Journal of biological chemistry
1960
Corpus ID: 6462920
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