Semantic Scholar uses AI to extract papers important to this topic.
There are currently no approved therapies for patients with metastatic pancreatic adenocarcinoma previously treated with… Expand BACKGROUND
Cancer control by radiotherapy (RT) can be improved with concurrent chemotherapy. Outpatient strategies for sarcomas… Expand AbsractPurposeTo evaluate safety and pharmacokinetics and to establish the maximum tolerated dose of glufosfamide when… Expand The oxazaphosphorines including cyclophosphamide (CPA), ifosfamide (IFO), and trofosfamide represent an important group of… Expand The oxazaphosphorines cyclophosphamide, ifosfamide and trofosfamide remain a clinically useful class of anticancer drugs with… Expand The activity of glufosfamide (beta-D-glucosylisophosphoramide mustard) was tested in a multicentre phase II clinical trial in… Expand BACKGROUND
Glufosfamide is a new alkylating agent in which the active metabolite of isophosphoramide mustard is covalently linked… Expand PURPOSE
To determine the maximum-tolerated dose (MTD), the principal toxicities, and the pharmacokinetics of 6-hour infusion of… Expand Some pharmaceuticals such as antineoplastics are carcinogenic, mutagenic, teratogenic and fetotoxic. Antineoplastics and their… Expand For beta-D-glucosylisophosphoramide mustard (beta-D-Glc-IPM), a new alkylating drug in which isophosphoramide mustard is… Expand