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glucosyl-ifosfamide mustard

Known as: Beta-D-Glucosyl-Ifosfamide Mustard, Glufosfamide, glc-IPM 
A compound consisting of the mustard agent ifosforamide conjugated to glucose, with potential alkylating activity. Glufosfamide is cleaved by… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
PURPOSE There are currently no approved therapies for patients with metastatic pancreatic adenocarcinoma previously treated with… Expand
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Review
2008
Review
2008
BACKGROUND Cancer control by radiotherapy (RT) can be improved with concurrent chemotherapy. Outpatient strategies for sarcomas… Expand
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2007
2007
AbsractPurposeTo evaluate safety and pharmacokinetics and to establish the maximum tolerated dose of glufosfamide when… Expand
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Review
2005
Review
2005
The oxazaphosphorines including cyclophosphamide (CPA), ifosfamide (IFO), and trofosfamide represent an important group of… Expand
Review
2005
Review
2005
The oxazaphosphorines cyclophosphamide, ifosfamide and trofosfamide remain a clinically useful class of anticancer drugs with… Expand
2004
2004
The activity of glufosfamide (beta-D-glucosylisophosphoramide mustard) was tested in a multicentre phase II clinical trial in… Expand
2003
2003
BACKGROUND Glufosfamide is a new alkylating agent in which the active metabolite of isophosphoramide mustard is covalently linked… Expand
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Highly Cited
2000
Highly Cited
2000
PURPOSE To determine the maximum-tolerated dose (MTD), the principal toxicities, and the pharmacokinetics of 6-hour infusion of… Expand
Highly Cited
2000
Highly Cited
2000
Some pharmaceuticals such as antineoplastics are carcinogenic, mutagenic, teratogenic and fetotoxic. Antineoplastics and their… Expand
Highly Cited
1998
Highly Cited
1998
For beta-D-glucosylisophosphoramide mustard (beta-D-Glc-IPM), a new alkylating drug in which isophosphoramide mustard is… Expand