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Prodrugs

Known as: Pro-Drugs, prodrug, Pro Drugs 
A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for… 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (1)

Drug Delivery Systems
aspects of radiation effectschemical synthesisstandards characteristics

Narrower (1)

glucosyl-ifosfamide mustard

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2009
Review
2009
Functional polymers as therapeutic agents: concept to market place.
Highly Cited
2009
Highly Cited
2009
Design, synthesis, and anti-HIV activity of 4'-modified carbocyclic nucleoside phosphonate reverse transcriptase inhibitors.
Review
2004
Review
2004
Cost-benefit analysis of capecitabine versus 5-fluorouracil/leucovorin in the treatment of colorectal cancer in the Netherlands.
2004
2004
Effects of four antiviral substances on lethal vaccinia virus (IHD strain) respiratory infections in mice.
Review
1999
Review
1999
New developments in sustained release drug delivery for the treatment of intraocular disease
Over the past 20 years, drug development has led to numerous medications with the potential to treat intraocular disease. These… 
Review
1998
Review
1998
Potential for selective modulation of glutathione in cancer chemotherapy.
Highly Cited
1998
Highly Cited
1998
Coupling of the antiviral agent zidovudine to polyaspartamide and in vitro drug release studies.
Highly Cited
1992
Highly Cited
1992
Repeated systemic administration of the mixed inhibitor of enkephalin-degrading enzymes, RB101, does not induce either antinociceptive tolerance or cross-tolerance with morphine.
Highly Cited
1988
Highly Cited
1988
Glycolamide esters as biolabile prodrugs of carboxylic acid agents: synthesis, stability, bioconversion, and physicochemical properties.
Benzoic acid esters of various substituted 2-hydroxyacetamides (glycolamides) were found to be hydrolyzed extremely rapidly in… 
Highly Cited
1982
Highly Cited
1982
Comparative assay of anticonvulsant and toxic potencies of sixteen GABAmimetic drugs
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