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Prodrugs

Known as: Pro-Drugs, prodrug, Pro Drugs 
A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Hypoxia is a state of low oxygen tension found in numerous solid tumours. It is typically associated with abnormal vasculature… Expand
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Review
2019
Review
2019
ABSTRACT Employing combination therapy has become obligatory in cancer cases exhibiting high tumor load, chemoresistant tumor… Expand
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Review
2019
Review
2019
The success of platinum-based anticancer agents has motivated the exploration of novel metal-based drugs for several decades… Expand
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Review
2018
Review
2018
There is a growing body of evidence to suggest that cannabinoids are beneficial for a range of clinical conditions, including… Expand
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Review
2018
Review
2018
Targeted nano-drug delivery systems conjugated with specific ligands to target selective cell-surface receptors or transporters… Expand
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Review
2017
Review
2017
Pancreatic ductal adenocarcinoma (PDAC), commonly referred to as pancreatic cancer, ranks among the leading causes of cancer… Expand
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Review
2008
Review
2008
Prodrugs are bioreversible derivatives of drug molecules that undergo an enzymatic and/or chemical transformation in vivo to… Expand
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Highly Cited
2008
Highly Cited
2008
It is known that many potent, often aromatic drugs are water insoluble, which has hampered their use for disease treatment. In… Expand
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Highly Cited
2008
Highly Cited
2008
Cisplatin is used to treat a variety of tumors, but dose limiting toxicities or intrinsic and acquired resistance limit its… Expand
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Highly Cited
1985
Highly Cited
1985
CONTENTS: 1. Design of prodrugs: Bioreversible derivatives for various functional groups and chemical entities (by H. Bundgaard… Expand
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