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gemcitabine triphosphate

National Institutes of Health

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Broader (1)

Cytidine Triphosphate
analogs & derivatives

Papers overview

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2018
2018
RALA-mediated dual delivery of pMIR-143 and gemcitabine triphosphate as a novel nanotherapy for the treatment of pancreatic cancer
2015
2015
Erratum to: Does saturable formation of gemcitabine triphosphate occur in patients?
2013
2013
Abstract 2378: Upregulation of the ATR/CHK1 pathway and decreased therapeutic sensitivity in upper aerodigestive cancer cell lines with distal 11q loss.
Gemcitabine, a pyrimidine analog/antimetabolite, is commonly used to treat breast, lung, head and neck, pancreatic, ovarian… 
2012
2012
Abstract 3494: Liver X receptor activation represents a novel strategy to block Hedgehog signaling in pancreatic adenocarcinoma and enhance the antitumor effect of gemcitabine
Background: The Hedgehog (Hh) signaling pathway plays a pathogenic role in many human cancers, including pancreatic… 
Review
2009
Review
2009
Pharmacokinetics of gemcitabine and metabolites in a patient with double-sided nephrectomy: a case report and review of the literature.
CASE A patient with complete renal failure as a result of urothelial cell carcinoma-related nephrectomy of both kidneys received… 
2007
2007
Questions about gemcitabine dose rate: answered or unanswered?
Even before 2 ,2 -difluorodeoxycytidine (dFdC) was given the name gemcitabine, laboratory studies were investigating the… 
Highly Cited
2006
Highly Cited
2006
Quantitative analysis of gemcitabine triphosphate in human peripheral blood mononuclear cells using weak anion-exchange liquid chromatography coupled with tandem mass spectrometry.
Gemcitabine triphosphate (dFdCTP) is a highly active metabolite of gemcitabine. It is formed intra-cellularly via the… 
Review
2004
Review
2004
Gemcitabine monotherapy in recurrent ovarian cancer: from the bench to the clinic
  • M. Bookman
  • International Journal of Gynecologic Cancer
  • 2004
  • Corpus ID: 38290730
Gemcitabine (2′2′-difluorodeoxycytidine [dFdC]) is a synthetic analog of deoxycytidine with two fluorine atoms at the 2′ position… 
2001
2001
Interference of gemcitabine triphosphate with the measurements of deoxynucleotides using an optimized DNA polymerase elongation assay.
The main mechanism of action of the anticancer drug gemcitabine is assumed to be incorporation of its triphosphate (dFdCTP) into… 
1997
1997
The role of gemcitabine in the treatment of small cell lung cancer
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