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fowlpox-TRICOM vaccine

Known as: Recombinant Fowlpox-TRICOM, rF-TRICOM (B7.1.iCAM1-LFA3-Fowlpox), Recombinant Fowlpox-TRICOM Vaccine 
A vaccine comprised of a recombinant fowlpox virus vector encoding a TRIad of COstimulatory Molecules (B7-1, ICAM-1 and LFA-3) (TRICOM), which may… Expand
National Institutes of Health

Papers overview

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Review
2010
Review
2010
Results from recent clinical trials of the therapeutic vaccines sipuleucel-T (Dendreon Corp), PROSTVAC-VF-TRICOM (National Cancer… Expand
2007
2007
Purpose: Interleukin (IL)-2 therapy is currently used for therapy of renal cell carcinoma (RCC). However, it is only effective in… Expand
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Highly Cited
2006
Highly Cited
2006
Successful immunotherapy of established tumors depends on overcoming the suppressive influence of the local tumor… Expand
2005
2005
The efficacy of antigen-specific CD8+ CTLs depends not only on the quantity of CTLs generated but also perhaps, more importantly… Expand
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2004
2004
Dendritic cells (DCs) are the most potent of the antigen-presenting cells (APCs). Preparation of sufficient numbers of mature DCs… Expand
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2004
2004
We demonstrated that enhanced expression of the costimulatory molecules CD80, CD54 and CD48 (designated rF-TRICOM) on target… Expand
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Highly Cited
2002
Highly Cited
2002
By virtue of its tissue-specific expression, carcinoembryonic antigen (CEA) is an important self, tumor-associated antigen, which… Expand
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Highly Cited
2001
Highly Cited
2001
T-cell activation usually requires at least two signals. The first signal is antigen-specific, and the second signal(s) involves… Expand
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2001
2001
  • M. Morse
  • Current opinion in molecular therapeutics
  • 2001
  • Corpus ID: 37668406
Therion Biologics, the NCI and Aventis Pasteur are investigating CEA-TRICOM, a recombinant, pox virus-based vaccine that… Expand