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fotrin

Known as: Photrin, 2,2,4,4,6-pentaethyleneimino-6-morpholinocyclotriphosphazatriene, 2,2,4,4,6-Pentaethylenimino-6-morpholino-cyclotriphosphazatrien 
A pentaethyleneimine derivative with antineoplastic alkylating activity. Fotretamine causes chromosomal breaks in lymphocytes which contributes to… 
National Institutes of Health

Related topics

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3 relations

Broader (3)

Antineoplastic Agents, AlkylatingAziridinesMutagens

Papers overview

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1995
1995
Study of photrin sorption by monocarboxycellulose
The sorption of photrin, an antitumor agent related to ethylenimine derivatives, by cellulose oxidized with nitrogen(IV) oxide… 
1993
1993
[The chromosomal sensitivity of hematopoietic cells in Xenopus laevis larvae to the action of the chemical mutagen fotrin].
Using the method of counting micronuclei it was shown that, in peripheral blood of larva of frog exposed to high doses of… 
1991
1991
[The effect of the interferon inducer ridostin on photrin-induced mutagenesis in bone marrow cells in mice].
The number of aberrant metaphases was used to assess the influence of a highly active interferon inducer--ridostin, a two-spiral… 
1991
1991
[The effect of the interferon inducer ridostin on photrin-induced mutagenesis in bone marrow cells in mice].
The number of aberrant metaphases was used to assess the influence of a highly active interferon inducer--ridostin, a two-spiral… 
1990
1990
[The cytogenetic effect of natural modifiers of mutagenesis in a human lymphocyte culture: the modification of the mutagenic effect by recombinant interferon in vitro in the lymphocytes of bronchial…
The significant protective effect of recombinant interferon in the cultures of lymphocytes of healthy donors and patients with… 
1988
1988
[Effect of interferon on the number of cytogenetic disorders occurring in human cultured lymphocytes treated with thio-TEPA and fotrin].
: The paper deals with the modifying effects of natural (leukocytic) and synthesized (recombinant) interferons on the number of… 
1985
1985
[Effect of dioxidine, antineoplastic agents and other mutagens on the precise excision of Tn1 and Tn10 transposons in E. coli K12].
Induction of precise excision of transposons Tn1 and Tn10 from the genes met::Tn1 and cys::Tn10 by chemical agents, having… 
1984
1984
[In vitro sensitivity of epidermoid lung cancer to cytostatics depending upon the degree of tumor differentiation].
In vitro sensitivity of epidermoid lung carcinoma to chemotherapeutic agents in short-term cultures versus degree of tumor… 
1976
1976
[Study of the decomposition of alkylating mutagens of the ethyleneimine series in human lymphocyte cultures].
A simple method of determination (with a high reproducibility) of concentrations of the alkylating compound in the culture medium… 
1976
1976
[Induction of dominant lethals in mice by fotrin].