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fosamprenavir

Known as: (3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-1-(phenylmethyl)-2-(phosphonooxy)propyl)carbamic acid C-(tetrahydro-3-furanyl) ester, fos-amprenavir, fosamprenavir [Chemical/Ingredient] 
A prodrug form of amprenavir. In the body fosamprenavir is metabolized to amprenavir, a synthetic derivative of hydroxyethylamine sulfonamide that… 
National Institutes of Health

Related topics

Related topics

14 relations
Amprenavir or Fosamprenavir:Susc:Pt:Isolate:OrdQn:GenotypingFosamprenavir SodiumFosamprenavir calciumFosamprenavir:Susc:Pt:Isolate:OrdQn:Phenotyping

Broader (5)

Anti-HIV AgentsCarbamatesHIV Protease InhibitorsOrganophosphates

Narrower (2)

GW-433908Lexiva

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
Transgender women, hormonal therapy and HIV treatment: a comprehensive review of the literature and recommendations for best practices
Studies have shown that transgender women (TGW) are disproportionately affected by HIV, with an estimated HIV prevalence of 19.1… 
Highly Cited
2016
Highly Cited
2016
Use of antiretroviral therapy and risk of end-stage liver disease and hepatocellular carcinoma in HIV-positive persons
Objectives:Although several antiretroviral drugs, including the d-drugs stavudine (d4T) and didanosine (ddI), may cause biomarker… 
Highly Cited
2009
Highly Cited
2009
Glucuronidation of the Antiretroviral Drug Efavirenz by UGT2B7 and an in Vitro Investigation of Drug-Drug Interaction with Zidovudine
The non-nucleoside reverse transcriptase inhibitor efavirenz (EFV) is directly conjugated by the UDP-glucuronosyltransferase (UGT… 
Highly Cited
2009
Highly Cited
2009
Changes in Cognition During Antiretroviral Therapy: Comparison of 2 Different Ranking Systems to Measure Antiretroviral Drug Efficacy on HIV-Associated Neurocognitive Disorders
Objective:Although HIV-associated neurocognitive disorders should be treated with highly active antiretroviral treatment (HAART… 
Review
2008
Review
2008
Drug interactions involving combination antiretroviral therapy and other anti-infective agents: repercussions for resource-limited countries.
X receptor (PXR) plays in human metabolism. A ligand such as rifampin (RIF) binds PXR, then forms a heterodimer with the 9-cis… 
Highly Cited
2007
Highly Cited
2007
Determination of 19 antiretroviral agents in pharmaceuticals or suspected products with two methods using high-performance liquid chromatography.
Highly Cited
2007
Highly Cited
2007
In vitro behavior of a phosphate ester prodrug of amprenavir in human intestinal fluids and in the Caco-2 system: illustration of intraluminal supersaturation.
Review
2006
Review
2006
Fosamprenavir : clinical pharmacokinetics and drug interactions of the amprenavir prodrug.
Fosamprenavir is one of the most recently approved HIV-1 protease inhibitors (PIs) and offers reductions in pill number and pill… 
Review
2005
Review
2005
Combining fosamprenavir with lopinavir/ritonavir substantially reduces amprenavir and lopinavir exposure: ACTG protocol A5143 results
Objective:To evaluate fosamprenavir/lopinavir (LPV)/ritonavir (RTV), fosamprenavir/RTV, or LPV/RTV in antiretroviral treatment… 
Highly Cited
2004
Highly Cited
2004
SOLO: 48-week efficacy and safety comparison of once-daily fosamprenavir /ritonavir versus twice-daily nelfinavir in naive HIV-1-infected patients
Objective: To compare the magnitude and durability of the antiviral response to fosamprenavir (FPV) plus ritonavir (RTV) once… 
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