Skip to search formSkip to main contentSkip to account menu

formestane

Known as: Formestano, 4-hydroxyandrostene-3,17-dione, 4-Hydroxyandrostenedione 
A synthetic steroidal substance with antineoplastic activity. Formestane binds irreversibly to and inhibits the enzyme aromatase, thereby blocking… 
National Institutes of Health

Related topics

Related topics

6 relations

Broader (3)

AndrostenedioneAntineoplastic AgentsAromatase Inhibitors

Narrower (1)

CGP 32349
NCIt Antineoplastic Agent Terminologyanalogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1995
Highly Cited
1995
Regulation of c-fos expression and TGF-β production by gonadal and adrenal androgens in normal human osteoblastic cells
Highly Cited
1994
Highly Cited
1994
Effects of steroidal and non steroidal aromatase inhibitors on sexual behavior and aromatase-immunoreactive cells and fibers in the quail brain
Highly Cited
1994
Highly Cited
1994
Role of P-450 aromatase in sex determination of the diamondback terrapin, Malaclemys terrapin.
Sex determination in the diamondback terrapin, Malaclemys terrapin, is temperature-dependent. Eggs incubated at 31 degrees C, and… 
Highly Cited
1993
Highly Cited
1993
MCF-7 human breast carcinomas in nude mice as a model for evaluating aromatase inhibitors
Review
1992
Review
1992
Aromatization inhibition alone or in combination with GnRH agonists for the treatment of premenopausal breast cancer patients
Review
1991
Review
1991
Aromatase and its inhibitors—an overview
1987
1987
Ovine placental aromatase: studies of activity levels, kinetic characteristics and effects of aromatase inhibitors.
1986
1986
Effect of 1,4,6-androstatriene-3,17-dione (ATD), 4-hydroxy-4-androstene-3,17-dione (4-OH-A) and 4-acetoxy-4-androstene-3,17-dione (4-Ac-A) on the 5 alpha-reduction of androgens in the rat prostate.
Highly Cited
1986
Highly Cited
1986
Development of a model for the induction of estrogen‐related prostatic hyperplasia in the dog and its response to the aromatase inhibitor 4‐hydroxy‐4‐androstene‐3,17‐dione: Preliminary results
Although the presence of the testes is an absolutely necessary prerequisite for benign prostatic hyperplasia (BPH) to occur, the… 
Highly Cited
1985
Highly Cited
1985
Steroid modulation of Mullerian duct regression in the chick embryo.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)