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flupirtine

Known as: ethyl 2-amino-6-((p-fluorobenzyl)amino)-3-pyridinecarbamate, ethyl N-(2-amino-6-((4-fluorophenyl)methylamino)pyridin-3-yl)carbamate, flupirtine [Chemical/Ingredient] 
National Institutes of Health

Related topics

Related topics

7 relations

Broader (2)

AminopyridinesAnalgesics

Narrower (5)

D 9998FLUPIRTINE GLUCONATEFLUPIRTINE MALEATEKatadolon

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Analgesic treatment of ciguatoxin-induced cold allodynia
2013
2013
Functional expression of KCNQ (Kv7) channels in guinea pig bladder smooth muscle and their contribution to spontaneous activity
The aim of the study was to determine whether KCNQ channels are functionally expressed in bladder smooth muscle cells (SMC) and… 
Review
2012
Review
2012
A Preliminary Review of its Pharmacodynamic and Pharmacokinetic Properties, and Therapeutic Potential in Acute and Chronic Pain States
Various sections of the manuscript reviewed by: E. A.lo", Institut fUr Anasthesiologie, Universitiitsspital, Ziirich, Switzerland… 
Highly Cited
2011
Highly Cited
2011
Transcriptional repression of the M channel subunit Kv7.2 in chronic nerve injury
Highly Cited
2007
Highly Cited
2007
Molecular expression and pharmacological identification of a role for Kv7 channels in murine vascular reactivity
This study represents a novel characterisation of KCNQ‐encoded potassium channels in the vasculature using a variety of… 
Highly Cited
2004
Highly Cited
2004
Pharmacological characterisation of acid-induced muscle allodynia in rats.
Highly Cited
1999
Highly Cited
1999
Flupirtine shows functional NMDA receptor antagonism by enhancing Mg2+ block via activation of voltage independent potassium channels
Summary. The spectrum of action of flupirtine includes analgesia, muscle relaxation and neuroprotection. N-methyl-D-aspartate… 
Review
1998
Review
1998
The b-wave of the electroretinogram as an index of retinal ischemia.
Highly Cited
1996
Highly Cited
1996
Protection of rabbit retina from ischemic injury by flupirtine.
PURPOSE The aim of this study was to determine wether flupirtine can slow down the changes seen in the rabbit retina after… 
Highly Cited
1995
Highly Cited
1995
The effects of D-23129, a new experimental anticonvulsant drug, on neurotransmitter amino acids in the rat hippocampus in vitro
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