flupirtine

Known as: ethyl 2-amino-6-((p-fluorobenzyl)amino)-3-pyridinecarbamate, ethyl N-(2-amino-6-((4-fluorophenyl)methylamino)pyridin-3-yl)carbamate, flupirtine [Chemical/Ingredient] 
 
National Institutes of Health

Papers overview

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Review
2013
Review
2013
Flupirtine was developed long before KV7 (KCNQ) channels were known. However, it was clear from the beginning that flupirtine is… (More)
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2012
2012
Flupirtine is neither an opioid nor a non steroidal anti-inflammatory drug (NSAID) producing its analgesic action through… (More)
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Review
2010
Review
2010
Flupirtine is a centrally acting, non-opioid analgesic that is available in a number of European countries for the treatment of a… (More)
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Review
2009
Review
2009
KCNQ genes encode five Kv7 K(+) channel subunits (Kv7.1-Kv7.5). Four of these (Kv7.2-Kv7.5) are expressed in the nervous system… (More)
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2006
2006
Retigabine and flupirtine are two structurally related molecules provided of anticonvulsant and analgesic actions. The present… (More)
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Highly Cited
2004
Highly Cited
2004
KCNQ subunits encode for the M current (I(KM)), a neuron-specific voltage-dependent K+ current with a well established role in… (More)
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1999
1999
The spectrum of action of flupirtine includes analgesia, muscle relaxation and neuroprotection. N-methyl-D-aspartate (NMDA… (More)
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1996
1996
PURPOSE The aim of this study was to determine wether flupirtine can slow down the changes seen in the rabbit retina after… (More)
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1991
1991
1. Flupirtine is a novel and, in all probability, centrally acting, analgesic. The present investigation was conducted in order… (More)
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1985
1985
The pharmacokinetics of the analgesic flupirtine (ethyl-N-[2-amino-6-(4-fluorophenylmethylamino)pyridin-3-yl] carbamate, D 9998… (More)
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