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fibrillin-1

Known as: fbn1, fibrillin-1 (FBN1), Fibrillin-1 [Chemical/Ingredient] 
A fibrillin (FBN1) that functions as a structural support protein for MICROFIBRILS. It also regulates the maturation of OSTEOBLASTS by controlling… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Stiff skin syndrome, an autosomal dominant congenital form of scleroderma, is caused by mutations in the domain of fibrillin-1… Expand
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Highly Cited
2009
Highly Cited
2009
Fibrillins constitute the major backbone of multifunctional microfibrils in elastic and nonelastic extracellular matrices. Proper… Expand
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Highly Cited
2008
Highly Cited
2008
Both latent transforming growth factor-β (TGF-β)-binding proteins fibrillins are components of microfibril networks, and both… Expand
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Highly Cited
2007
Highly Cited
2007
We have discovered that fibrillin-1, which forms extracellular microfibrils, can regulate the bioavailability of transforming… Expand
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Highly Cited
2003
Highly Cited
2003
Latent transforming growth factor β-binding protein 1 (LTBP-1) targets latent complexes of transforming growth factor β to the… Expand
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Highly Cited
2003
Highly Cited
2003
Marfan syndrome is an autosomal dominant disorder of connective tissue caused by mutations in fibrillin-1 (encoded by FBN1 in… Expand
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Highly Cited
2003
Highly Cited
2003
Weill-Marchesani syndrome (WMS) is a connective tissue disorder characterised by short stature, brachydactyly, joint stiffness… Expand
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Highly Cited
1999
Highly Cited
1999
Dissecting aortic aneurysm is the hallmark of Marfan syndrome (MFS) and the result of mutations in fibrillin-1, the major… Expand
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Highly Cited
1997
Highly Cited
1997
Aortic aneurysm and dissection account for about 2% of all deaths in industrialized countries; they are also components of… Expand
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Highly Cited
1994
Highly Cited
1994
During the previous cloning of the fibrillin gene (FBN1), we isolated a partial cDNA coding for a fibrillin-like peptide and… Expand
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