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epostane
Known as:
4,5-epoxy-3,17-dihydroxy-4,17-dimethylandrost-2-ene-2-carbonitrile (4alpha,5alpha,17beta)
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Abortifacient Agents, Steroidal
Androstenols
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Structure/function aspects of human 3β-hydroxysteroid dehydrogenase
James L. Thomas
,
W. Duax
,
A. Addlagatta
,
B. Kacsoh
,
Stacey Brandt
,
W. Norris
Molecular and Cellular Endocrinology
2004
Corpus ID: 37047654
Highly Cited
2001
Highly Cited
2001
Ventral Tegmental Area Infusions of Inhibitors of the Biosynthesis and Metabolism of 3α,5α‐THP Attenuate Lordosis of Hormone‐Primed and Behavioural Oestrous Rats and Hamsters
C. Frye
,
J. M. Vongher
Journal of neuroendocrinology
2001
Corpus ID: 45737849
The importance of progesterone biosynthesis and metabolism to 5α‐pregnan‐3α‐ol‐20‐one (3α,5α‐THP), which exerts its effects via…
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2001
2001
Periovulatory changes in catfish ovarian oestradiol-17beta, oestrogen-2-hydroxylase and catechol-O-methyltransferase during GnRH analogue-induced ovulation and in vitro induction of oocyte maturation…
B. Senthilkumaran
,
K. Joy
Journal of Endocrinology
2001
Corpus ID: 23773620
In the catfish Heteropneustes fossilis and Clarias batrachus, ovarian oestrogen-2-hydroxylase (OE-2-H) activity increased…
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1997
1997
Inhibition and augmentation of progesterone production during pregnancy: effects on parturition in rhesus monkeys.
G. Haluska
,
Michael J. Cooka
,
M. Novy
American Journal of Obstetrics and Gynecology
1997
Corpus ID: 23847080
Highly Cited
1991
Highly Cited
1991
Comparison of inhibitory actions of indomethacin and epostane on ovulation in rats.
N. Tanaka
,
L. Espey
,
T. Kawano
,
H. Okamura
American Journal of Physiology
1991
Corpus ID: 38999536
Indomethacin, an inhibitor of cyclooxygenase that generates prostaglandins (PGs) from arachidonic acid, and 2 alpha,4 alpha,7-4,5…
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1990
1990
Inhibitory effect of synthetic progestins, 4-MA and cyanoketone on human placental 3β-hydroxysteroid dehydrogenase/5→4-ene-isomerase activity
Masakazu Takahashi
,
V. Luu‐The
,
F. Labrie
Journal of Steroid Biochemistry and Molecular…
1990
Corpus ID: 24730419
1988
1988
Termination of early pregnancy by the 3 beta-hydroxysteroid dehydrogenase inhibitor epostane.
M. Crooij
,
C. De Nooyer
,
B. Rao
,
GERRIT T. Berends
,
L. Gooren
,
J. Janssens
New England Journal of Medicine
1988
Corpus ID: 12355765
Progesterone is essential to sustain pregnancy in the first eight weeks. Its synthesis requires the enzyme 3 beta-hydroxysteroid…
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1985
1985
Interruption of first trimester human pregnancy following Epostane therapy. Effect of prostaglandin E2 pessaries
M. Webster
,
S. Phipps
,
M. Gillmer
British Journal of Obstetrics and Gynaecology
1985
Corpus ID: 22724987
Summary. The effect of Epostane, a competitive inhibitor of the 3β hydroxy steroid dehydrogenase enzyme system in combination…
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1985
1985
A simple in vitro approach to the estimation of the biopotency of drugs affecting adrenal steroidogenesis.
A. Lambert
,
R. Mitchell
,
J. Frost
,
W. Robertson
Journal of Steroid Biochemistry
1985
Corpus ID: 5976213
1985
1985
Myometrial activity in first trimester human pregnancy after Epostane therapy. Effect of intravenous oxytocin
M. Webster
,
N. Pattison
,
S. Phipps
,
M. Gillmer
British Journal of Obstetrics and Gynaecology
1985
Corpus ID: 1467350
Summary. The effect on myometrial activity of Epostane, a competitive inhibitor of the 3β‐hydroxy steroid dehydrogenase enzyme…
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