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elinafide
Known as:
N,N'-(Trimethylenebis(iminoethylene))dinaphthalimide
A symmetrical dimeric bis-naphthalimide compound and a topoisomerase II inhibitor with antineoplastic activity. Elinafide contains two neutral…
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National Institutes of Health
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Related topics
Related topics
3 relations
Broader (2)
Amides
Isoquinolines
Narrower (1)
LU 79553
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Analysis of mixed DNA-bisnaphthalimide interactions involving groove association and intercalation with surface-based and solution methodologies.
Luis González-Bulnes
,
J. Gallego
Biopolymers
2012
Corpus ID: 24902612
The bisnaphthalimide cytotoxic agent elinafide exhibits a mixed DNA binding mode including groove-association and intercalation…
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2009
2009
Indirect effects modulating the interaction between DNA and a cytotoxic bisnaphthalimide reveal a two-step binding process.
Luis González-Bulnes
,
J. Gallego
Journal of the American Chemical Society
2009
Corpus ID: 19774449
The sequence-specific structural and dynamic properties of double-helical DNA play important roles in many biological processes…
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Highly Cited
2004
Highly Cited
2004
New analogues of amonafide and elinafide, containing aromatic heterocycles: synthesis, antitumor activity, molecular modeling, and DNA binding properties.
M. Braña
,
Mónica Cacho
,
+9 authors
J. Lacal
Journal of Medicinal Chemistry
2004
Corpus ID: 39563245
Amonafide- and elinafide-related mono and bisintercalators, modified by the introduction of a pi-excedent furan or thiophene ring…
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Highly Cited
2003
Highly Cited
2003
Synthesis, biological evaluation and DNA binding properties of novel mono and bisnaphthalimides.
M. Braña
,
Mónica Cacho
,
+7 authors
C. Bailly
Organic and biomolecular chemistry
2003
Corpus ID: 1277591
A novel series of mono and bisnaphthalimides was synthesized and their antiproliferative activities were evaluated against three…
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Review
2003
Review
2003
The biological activities of new polyamine derivatives as potential therapeutic agents.
P. Lin
,
A. Dance
,
C. Bestwick
,
L. Milne
Biochemical Society Transactions
2003
Corpus ID: 22665540
A number of polyamine derivatives have demonstrated potential as therapeutic agents. For example, 1,12-bisethylspermine and…
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