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ectonucleoside triphosphate diphosphohydrolase 1

Known as: Vascular ATP Diphosphohydrolase, EC 3.6.1.5, CD39 
Ectonucleoside triphosphate diphosphohydrolase 1 (510 aa, ~58 kDa) is encoded by the human ENTPD1 gene. This protein is involved in the activation of… 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (2)

ApyraseCD Antigens
ENTPD1 geneEnzyme GeneHydrolysis

Papers overview

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Highly Cited
2006
Highly Cited
2006
RanBPM associates with CD39 and modulates ecto-nucleotidase activity.
CD39/ecto-NTPDase 1 (nucleoside triphosphate diphosphohydrolase 1) is an ecto-nucleotidase that influences P2 receptor activation… 
Highly Cited
2003
Highly Cited
2003
Purification and characterization of NTPDase1 (ecto-apyrase) and NTPDase2 (ecto-ATPase) from porcine brain cortex synaptosomes.
We purified to homogeneity and characterized NTPDase1 and NTPDase2 from porcine brain cortex synaptosomes. SDS/PAGE and… 
Highly Cited
2002
Highly Cited
2002
Adenine nucleotide analogues locked in a Northern methanocarba conformation: enhanced stability and potency as P2Y(1) receptor agonists.
Preference for the Northern (N) ring conformation of the ribose moiety of nucleotide 5'-triphosphate agonists at P2Y(1), P2Y(2… 
2000
2000
Signal-transducing mechanisms involved in activation of the platelet collagen receptor integrin alpha(2)beta(1).
Evidence was obtained about the mechanism responsible for platelet integrin alpha(2)beta activation by determining effects of… 
Highly Cited
1999
Highly Cited
1999
Glycosylation is essential for functional expression of a human brain ecto-apyrase.
The importance of N-linked glycosylation for the function and oligomerization of an E-type ATPase was examined by using… 
Highly Cited
1997
Highly Cited
1997
Stage-specific expression of P2Y receptors, ecto-apyrase, and ecto-5'-nucleotidase in myeloid leukocytes.
The expression of P2 purinergic receptor subtypes in leukocytes varies with both lineage and developmental stage. Given the… 
Highly Cited
1991
Highly Cited
1991
Characterization of a synaptosomal ATP diphosphohydrolase from the electric organ of Torpedo marmorata
1980
1980
Extracellular ATP, ecto‐ATPase and calcium influx in Dictyostelium discoideum cells
Highly Cited
1971
Highly Cited
1971
Influence of Apyrase on Stability of Suspensions of Washed Rabbit Platelets
Summary The addition of apyrase to suspensions of washed rabbit platelets stored at 37° maintains their sensitivity to ADP… 
Highly Cited
1967
Highly Cited
1967
Free adenosine diphosphate as an intermediary in the phosphorylation by creatine phosphate of adenosine diphosphate bound to actin.
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