ectonucleoside triphosphate diphosphohydrolase 1

Known as: Vascular ATP Diphosphohydrolase, EC 3.6.1.5, CD39 
Ectonucleoside triphosphate diphosphohydrolase 1 (510 aa, ~58 kDa) is encoded by the human ENTPD1 gene. This protein is involved in the activation of… (More)

Topic mentions per year

Topic mentions per year

1947-2018
020406019472017

Papers overview

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2010
2010
CD39 is a transmembrane enzyme that inhibits platelet reactivity and inflammation by phosphohydrolyzing ATP and ADP to AMP… (More)
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Highly Cited
2009
Highly Cited
2009
Despite the fact that CD4(+)CD25(+)Foxp3(+) regulatory T cells (Treg cells) play a central role in maintaining self-tolerance and… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Extracellular adenosine, generated from extracellular nucleotides via ectonucleotidases, binds to specific receptors… (More)
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Highly Cited
2007
Highly Cited
2007
The study of T regulatory cells (T reg cells) has been limited by the lack of specific surface markers and an inability to define… (More)
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2007
2007
We previously reported that ATP coreleased with norepinephrine from cardiac sympathetic nerves activates presynaptic P2X… (More)
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2005
2005
Using a guinea pig heart synaptosomal preparation, we previously observed that norepinephrine (NE) exocytosis was attenuated by a… (More)
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Highly Cited
2002
Highly Cited
2002
Under conditions of limited oxygen availability (hypoxia), multiple cell types release adenine nucleotides in the form of ATP… (More)
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Highly Cited
2002
Highly Cited
2002
CD39, the endothelial ecto-nucleoside triphosphate diphosphohydrolase (NTPDase), regulates vascular inflammation and thrombosis… (More)
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Highly Cited
1999
Highly Cited
1999
CD39, or vascular adenosine triphosphate diphosphohydrolase, has been considered an important inhibitor of platelet activation… (More)
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Highly Cited
1996
Highly Cited
1996
Vascular ATP diphosphohydrolase (ATPDase) is a plasma membrane-bound enzyme that hydrolyses extracellular ATP and ADP to AMP… (More)
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