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ectonucleoside triphosphate diphosphohydrolase 1

Known as: Vascular ATP Diphosphohydrolase, EC 3.6.1.5, CD39 
Ectonucleoside triphosphate diphosphohydrolase 1 (510 aa, ~58 kDa) is encoded by the human ENTPD1 gene. This protein is involved in the activation of… 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (2)

ApyraseCD Antigens
ENTPD1 geneEnzyme GeneHydrolysis

Papers overview

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Review
2010
Review
2010
Extracellular adenosine triphosphate and adenosine in cancer
Adenosine triphosphate (ATP) is actively released in the extracellular environment in response to tissue damage and cellular… 
Highly Cited
2007
Highly Cited
2007
CD39/Ectonucleoside Triphosphate Diphosphohydrolase 1 Provides Myocardial Protection During Cardiac Ischemia/Reperfusion Injury
Background— Extracellular adenosine, generated from extracellular nucleotides via ectonucleotidases, binds to specific receptors… 
Highly Cited
2005
Highly Cited
2005
Comparative hydrolysis of P2 receptor agonists by NTPDases 1, 2, 3 and 8
Nucleoside triphosphate diphosphohydrolases 1, 2, 3 and 8 (NTPDases 1, 2, 3 and 8) are the dominant ectonucleotidases and thereby… 
Highly Cited
2004
Highly Cited
2004
A Novel P2X7 Receptor Activator, the Human Cathelicidin-Derived Peptide LL37, Induces IL-1β Processing and Release1
The release of IL-1β is a tightly controlled process that requires induced synthesis of the precursor pro-IL-1β and a second… 
Highly Cited
2004
Highly Cited
2004
Fluid Shear‐Induced ATP Secretion Mediates Prostaglandin Release in MC3T3‐E1 Osteoblasts
ATP is rapidly released from osteoblasts in response to mechanical load. We examined the mechanisms involved in this release and… 
Highly Cited
1996
Highly Cited
1996
Purification and cloning of a soluble ATP-diphosphohydrolase (apyrase) from potato tubers (Solanum tuberosum).
A soluble ATP-diphosphohydrolase (apyrase, EC 3.6.1.5) has been purified from potato tubers. Solanum tuberosum, to a specific… 
Highly Cited
1996
Highly Cited
1996
CD39 Is an Ecto-(Ca,Mg)-apyrase (*)
CD39, a 70- to 100-kDa molecule expressed primarily on activated lymphoid cells, was previously identified as a surface marker of… 
Highly Cited
1974
Highly Cited
1974
Adenosine triphosphate. A constituent of cholinergic synaptic vesicles.
1. Synaptic vesicles separated by density-gradient centrifugation from extracts of the cholinergic nerve terminals of the… 
Highly Cited
1961
Highly Cited
1961
Studies on apyrases.
Review
1952
Review
1952
Firefly luminescence in the study of energy transfer mechanisms. I. Substrate and enzyme determination.
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