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Apyrase
Known as:
ATP diphosphohydrolase
, ATP Diphosphatase
, ADPase
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A calcium-activated enzyme that catalyzes the hydrolysis of ATP to yield AMP and orthophosphate. It can also act on ADP and other nucleoside…
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National Institutes of Health
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Related topics
Related topics
12 relations
ENTPD1 gene
In Blood
Process of secretion
adenosine-diphosphatase activity
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Narrower (3)
apyrase activity
apyrase-2, Dolichos biflorus
ectonucleoside triphosphate diphosphohydrolase 1
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Pimecrolimus does not affect Langerhans cells in murine epidermis
J. Meingassner
,
E. Kowalsky
,
H. Schwendinger
,
A. Elbe-Bürger
,
A. Stütz
British Journal of Dermatology
2003
Corpus ID: 26517363
Background Langerhans cells (LCs) function as specialized antigen‐presenting cells in the epidermis, and therefore play a…
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2001
2001
Multiple ecto‐nucleotidases in PC12 cells: identification and cellular distribution after heterologous expression
Petra Vollmayer
,
M. Koch
,
+5 authors
H. Zimmermann
Journal of Neurochemistry
2001
Corpus ID: 2446454
The physiological action of extracellular ATP and other nucleotides in the nervous system is controlled by surface‐located…
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Highly Cited
2000
Highly Cited
2000
CD39L2, a gene encoding a human nucleoside diphosphatase, predominantly expressed in the heart.
George Yeung
,
J. Mulero
,
Daniel W. McGowan
,
Sanjeev S. Bajwa
,
John E. Ford
Biochemistry
2000
Corpus ID: 12295944
E-NTPDases are extracellular enzymes that hydrolyze nucleotides. The human E-NTPDase gene family currently consists of five…
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Highly Cited
1994
Highly Cited
1994
Oxygen-induced retinopathy in the rat: relationship of retinal nonperfusion to subsequent neovascularization.
John S. Penn
,
B. Tolman
,
M. M. Henry
Investigative Ophthalmology and Visual Science
1994
Corpus ID: 4696700
PURPOSE To confirm a relationship between oxygen-induced retinal vasoattenuation and subsequent abnormal neovascularization in…
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Highly Cited
1993
Highly Cited
1993
Differentiation of dendritic cell populations in macrophage colony‐stimulating factor‐deficient mice homozygous for the osteopetrosis (op) mutation
Kiyoshi Takahashi
,
M. Naito
,
L. Shultz
,
S. Hayashi
,
S. Nishikawa
Journal of Leukocyte Biology
1993
Corpus ID: 15142014
In op/op mice, immunohistochemical and electron microscopic techniques were used to examine the effects of the OP mutation on…
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Highly Cited
1992
Highly Cited
1992
Modulation of anti-Thy1 nephritis in the rat by adenine nucleotides. Evidence for an anti-inflammatory role for nucleotidases.
K. Poelstra
,
E. Heynen
,
J. Baller
,
M. Hardonk
,
W. Bakker
Laboratory investigation; a journal of technical…
1992
Corpus ID: 26138569
Extracellular adenine nucleotides are considered mediators of inflammation because they modulate functions of neutrophils and…
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Highly Cited
1992
Highly Cited
1992
Regulation of extracellular adenosine production by ectonucleotidases of adult rat ventricular myocytes.
P. Meghji
,
J. Pearson
,
L. Slakey
American Journal of Physiology
1992
Corpus ID: 21112005
We have investigated the kinetic properties of the extracellular reaction sequence ATP----ADP----AMP----adenosine catalyzed by…
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1988
1988
Demonstration of a novel ecto-enzyme on human erythrocytes, capable of degrading ADP and of inhibiting ADP-induced platelet aggregation.
J. Lüthje
,
A. Schomburg
,
A. Ogilvie
European Journal of Biochemistry
1988
Corpus ID: 25932720
The role of ADP as an important inducer of platelet aggregation is generally accepted. Therefore it has been postulated by many…
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Highly Cited
1987
Highly Cited
1987
Characterization of a potent platelet aggregation inhibitor from Agkistrodon rhodostoma snake venom.
Tur-Fu Huang
,
Yong-Ji Wu
,
C. Ouyang
Biochimica et Biophysica Acta
1987
Corpus ID: 25895109
Highly Cited
1971
Highly Cited
1971
COMPOSITION OF CELLULAR MEMBRANES IN THE PANCREAS OF THE GUINEA PIG
J. Meldolesi
,
J. D. Jamieson
,
G. Palade
Journal of Cell Biology
1971
Corpus ID: 47292123
A comparative study of the enzymic activities of membrane fractions derived from guinea pig pancreatic homogenates has yielded…
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