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Apyrase

Known as: ATP diphosphohydrolase, ATP Diphosphatase, ADPase 
A calcium-activated enzyme that catalyzes the hydrolysis of ATP to yield AMP and orthophosphate. It can also act on ADP and other nucleoside… 
National Institutes of Health

Related topics

Related topics

12 relations
ENTPD1 geneIn BloodProcess of secretionadenosine-diphosphatase activity

Narrower (3)

apyrase activityapyrase-2, Dolichos biflorusectonucleoside triphosphate diphosphohydrolase 1

Papers overview

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Highly Cited
2003
Highly Cited
2003
Pimecrolimus does not affect Langerhans cells in murine epidermis
Background  Langerhans cells (LCs) function as specialized antigen‐presenting cells in the epidermis, and therefore play a… 
Highly Cited
2003
Highly Cited
2003
Human Airway Ecto-adenylate Kinase
Mechanically induced ATP release from human airway epithelial cells regulates mucociliary clearance through cell surface… 
2001
2001
Multiple ecto‐nucleotidases in PC12 cells: identification and cellular distribution after heterologous expression
The physiological action of extracellular ATP and other nucleotides in the nervous system is controlled by surface‐located… 
1995
1995
Inhibition of extracellular ATP degradation in endothelial cells.
Highly Cited
1993
Highly Cited
1993
Differentiation of dendritic cell populations in macrophage colony‐stimulating factor‐deficient mice homozygous for the osteopetrosis (op) mutation
In op/op mice, immunohistochemical and electron microscopic techniques were used to examine the effects of the OP mutation on… 
Highly Cited
1992
Highly Cited
1992
Modulation of anti-Thy1 nephritis in the rat by adenine nucleotides. Evidence for an anti-inflammatory role for nucleotidases.
Extracellular adenine nucleotides are considered mediators of inflammation because they modulate functions of neutrophils and… 
1988
1988
Demonstration of a novel ecto-enzyme on human erythrocytes, capable of degrading ADP and of inhibiting ADP-induced platelet aggregation.
The role of ADP as an important inducer of platelet aggregation is generally accepted. Therefore it has been postulated by many… 
Highly Cited
1987
Highly Cited
1987
Characterization of a potent platelet aggregation inhibitor from Agkistrodon rhodostoma snake venom.
1984
1984
Characterization and localization of the ATPase associated with pea chloroplast envelope membranes.
Chloroplast envelope membranes isolated from Pisum sativum seedlings have been found to contain a Mg-ATPase activity (specific… 
Highly Cited
1971
Highly Cited
1971
COMPOSITION OF CELLULAR MEMBRANES IN THE PANCREAS OF THE GUINEA PIG
A comparative study of the enzymic activities of membrane fractions derived from guinea pig pancreatic homogenates has yielded… 
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