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ecarin

Known as: echarin, Echis carinatus prothrombin-activating proteins, prothrombin activator (Echis carinatus venom) 
National Institutes of Health

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2 relations

Broader (2)

EndopeptidasesFibrinolytic Agents

Papers overview

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2003
2003
Structural characterization of EMS16, an antagonist of collagen receptor (GPIa/IIa) from the venom of Echis multisquamatus.
Snake venoms contain a number of hemostatically active C-type lectin-like proteins (CLPs), which affect the blood coagulation… 
Highly Cited
2001
Highly Cited
2001
Echicetin, a GPIb-binding snake C-type lectin from Echis carinatus, also contains a binding site for IgMkappa responsible for platelet agglutination in plasma and inducing signal transduction.
Echicetin, a heterodimeric snake C-type lectin from Echis carinatus, is known to bind specifically to platelet glycoprotein (GP… 
1997
1997
Amino acid sequence of the alpha subunit and computer modelling of the alpha and beta subunits of echicetin from the venom of Echis carinatus (saw-scaled viper).
Echicetin, a heterodimeric protein from the venom of Echis carinatus, binds to platelet glycoprotein Ib (GPIb) and so inhibits… 
1995
1995
Prothrombin conversion intermediate effectively neutralizes toxic levels of hirudin.
1992
1992
Gene expression in Echis carinatus (carpet viper) venom glands following milking.
1990
1990
The active site of membrane-bound meizothrombin. A fluorescence determination of its distance from the phospholipid surface and its conformational sensitivity to calcium and factor Va.
1990
1990
Prevention of Canine Coronary Artery Thrombosis with Echistatin, a Potent Inhibitor of Platelet Aggregation from the Venom of the Viper, Echis carmatus
Summary A model of acute, platelet-dependent canine coronary artery thrombosis was utilized to assess the antithrombotic effect… 
Highly Cited
1989
Highly Cited
1989
Chemical synthesis of echistatin, a potent inhibitor of platelet aggregation from Echis carinatus: synthesis and biological activity of selected analogs.
Echistatin, a polypeptide from the venom of the saw-scaled viper, Echis carinatus, containing 49 amino acids and 4 cystine… 
Highly Cited
1973
Highly Cited
1973
Mechanism of Action of Vitamin K: Demonstration of a Liver Precursor of Prothrombin
Extracts of sonicated liver microsomes that are prepared from rats deficient in vitamin K or from rats given vitamin K… 
1973
1973
A rat liver protein with potential thrombin activity: properties and partial purification.
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