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ecadotril

Known as: acetorphan, (S)-isomer, sinorphan 
National Institutes of Health

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1 relation

Broader (1)

racecadotril

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Intrinsic defence capacity and therapeutic potential of natriuretic peptides in pulmonary hypertension associated with lung fibrosis
Idiopathic pulmonary fibrosis (IPF) is a progressive fibro‐proliferative disorder refractory to current therapy commonly… 
2004
2004
The Effect of Acute Angiotensin-Converting Enzyme and Neutral Endopeptidase 24.11 Inhibition on Plasma Extravasation in the Rat
The effect of angiotensin-converting enzyme (ACE) and neutral endopeptidase (NEP) inhibition on microvascular plasma leakage… 
2000
2000
Effects of chronic neutral endopeptidase inhibition in rats with cyclosporine‐induced hypertension
Objective Cyclosporine (CysA), a potent immunosuppressant, is associated with hypertension and nephrotoxicity. Neutral… 
1999
1999
Novel Neurohormonal Modulators in Cardiovascular Disorders
Since angiotensin II is an established target of pharmacological interventions, there is an increasing interest in the biological… 
Review
1999
Review
1999
Novel neurohormonal modulators in cardiovascular disorders. The therapeutic potential of endopeptidase inhibitors.
Since angiotensin II is an established target of pharmacological interventions, there is an increasing interest in the biological… 
1995
1995
Prolonged inhibition of neutral endopeptidase 24.11 by sinorphan in stroke-prone spontaneously hypertensive rats.
The cardiovascular consequences of inhibition of the neutral endopeptidase 24.11 (NEP) with the orally active NEP inhibitor… 
1995
1995
Sinorphan Improves Cardiac Structure and Function in Aged Stroke-Prone Spontaneously Hypertensive Rats
Inhibition of atrial natriuretic peptide (ANP) degradation by enkephalinase is known to increase endogenous ANP levels and to… 
1993
1993
Inhibition of neutral endopeptidase stimulates renal sodium excretion in patients with chronic renal failure.
1. The acute effects of a single oral dose of sinorphan (100 mg), an inhibitor of neutral endopeptidase, on the plasma atrial… 
Review
1991
Review
1991
[New approach in the research of analgesics and antihypertensive agents].
The activation or interruption of the responses induced by regulatory peptides are ensured by ectoenzymes, the most important of… 
1990
1990
Degradation of atrial natriuretic factor in mouse blood in vitro and in vivo: Role of enkephalinase (EC 3.4.24.11)
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