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ecadotril

Known as: acetorphan, (S)-isomer, sinorphan 
National Institutes of Health

Papers overview

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Review
2014
Review
2014
Neprilysin is an enzyme that contributes to the breakdown of the biologically active natriuretic peptides and several other… Expand
  • table 1
1999
1999
OBJECTIVE To determine the short-term safety and tolerability of the addition of ecadotril to conventional therapy in patients… Expand
Highly Cited
1998
Highly Cited
1998
The combination of neutral endopeptidase 24.11 (NEP) and angiotensin converting enzyme (ACE) inhibition is a candidate therapy… Expand
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Highly Cited
1995
Highly Cited
1995
Objective: To evaluate the antihypertensive efficacy of sinorphan, an orally active inhibitor of neutral endopeptidase EC 3.4.24… Expand
1993
1993
1. The acute effects of a single oral dose of sinorphan (100 mg), an inhibitor of neutral endopeptidase, on the plasma atrial… Expand
1991
1991
We examined the acute effects of sinorphan, an inhibitor of enkephalinase, on plasma atrial natriuretic factor (ANF) and urinary… Expand
Highly Cited
1990
1990
1990
1990
1990
We compared the relative potencies of sinorphan and retorphan, the S- and R-enantiomers of acetorphan a potent inhibitor of… Expand
1990
1990
The half-life of 125I-ANF (99-126) in mouse blood in vivo, evaluated after HPLC analysis, was approximately 0.5 min. This value… Expand