Semantic Scholar uses AI to extract papers important to this topic.
Neprilysin is an enzyme that contributes to the breakdown of the biologically active natriuretic peptides and several other… Expand OBJECTIVE
To determine the short-term safety and tolerability of the addition of ecadotril to conventional therapy in patients… Expand The combination of neutral endopeptidase 24.11 (NEP) and angiotensin converting enzyme (ACE) inhibition is a candidate therapy… Expand Objective: To evaluate the antihypertensive efficacy of sinorphan, an orally active inhibitor of neutral endopeptidase EC 3.4.24… Expand 1. The acute effects of a single oral dose of sinorphan (100 mg), an inhibitor of neutral endopeptidase, on the plasma atrial… Expand We examined the acute effects of sinorphan, an inhibitor of enkephalinase, on plasma atrial natriuretic factor (ANF) and urinary… Expand We compared the relative potencies of sinorphan and retorphan, the S- and R-enantiomers of acetorphan a potent inhibitor of… Expand The half-life of 125I-ANF (99-126) in mouse blood in vivo, evaluated after HPLC analysis, was approximately 0.5 min. This value… Expand