FAQ

ecadotril

Known as: acetorphan, (S)-isomer, sinorphan 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2014
02419902014

Related topics

Related topics

1 relation

Broader (1)

racecadotril

Related mentions per year

Related mentions per year

1986-2018
19801990200020102020
ecadotril
racecadotril

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2000
2000
Intrarenal effects of ecadotril during acute volume expansion in dogs with congestive heart failure.
Neutral endopeptidase 24.11 (NEP) inhibitors are known to have vascular, diuretic, and natriuretic effects that may be helpful in… (More)
  • figure 1
  • figure 3
  • figure 2
  • figure 5
  • figure 4
Is this relevant?
2000
2000
Acute, subchronic, and chronic toxicity of ecadotril in dogs.
OBJECTIVE To determine the toxicity of ecadotril in dogs. ANIMALS 74 healthy 4- to 11-month-old Beagles. PROCEDURE To… (More)
Is this relevant?
1999
1999
A randomized trial of ecadotril versus placebo in patients with mild to moderate heart failure: the U.S. ecadotril pilot safety study.
OBJECTIVE To determine the short-term safety and tolerability of the addition of ecadotril to conventional therapy in patients… (More)
Is this relevant?
1998
1998
Effect of ecadotril, a neutral endopeptidase inhibitor, on myocardial hypertrophy in the rat aortic insufficiency model.
Cardiac hypertrophy develops to compensate for hemodynamic overload of the myocardium. However, cardiac hypertrophy itself poses… (More)
Is this relevant?
1995
1995
Neutral endopeptidase versus angiotensin converting enzyme inhibition in essential hypertension.
OBJECTIVE To evaluate the antihypertensive efficacy of sinorphan, an orally active inhibitor of neutral endopeptidase EC 3.4.24… (More)
Is this relevant?
1994
1994
Acute renal effects of neutral endopeptidase inhibition in humans.
The acute renal effects of neutral endopeptidase 24.11 (E-24.11) inhibition induced by a single oral dose of sinorphan (100 mg… (More)
Is this relevant?
1993
1993
Inhibition of neutral endopeptidase stimulates renal sodium excretion in patients with chronic renal failure.
1. The acute effects of a single oral dose of sinorphan (100 mg), an inhibitor of neutral endopeptidase, on the plasma atrial… (More)
Is this relevant?
1991
1991
Effect of sinorphan, an enkephalinase inhibitor, on plasma atrial natriuretic factor and sodium urinary excretion in cirrhotic patients with ascites.
We examined the acute effects of sinorphan, an inhibitor of enkephalinase, on plasma atrial natriuretic factor (ANF) and urinary… (More)
Is this relevant?
1990
1990
Antihypertensive activity of sinorphan.
 
Is this relevant?
1990
1990
Effect of sinorphan on plasma atrial natriuretic factor in congestive heart failure.
 
Is this relevant?