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ecabapide

Known as: 3-2-2-(3,4-dimethoxyphenyl)ethylamino-2-oxoethylamino-N-methylbenzamide, Benzamide, 3-((2-((2-(3,4-dimethoxyphenyl)ethyl)amino)-2-oxoethyl)amino)-N-methyl- 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

Anti-Ulcer AgentBenzamides

Narrower (1)

DQ 2511

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Involvement of the Neurokinin-2 Receptor in Airway Smooth Muscle Stretch-Activated Contractions Assessed in Perfused Intact Bovine Bronchial Segments
The airway response to deep inspirations (DIs) in asthmatics has been shown to be ineffective in producing bronchodilation and… 
2006
2006
Composition useful to treat e.g. anxiety disorder comprises (S)-(-)-N-(4-(4-acetamido-4-phenyl-1-piperidyl)-2-(3, 4-dichlorophenyl) butyl)-N-methylbenzamide, (plus minus)-N-methyl-3-phenyl-3-(4…
2003
2003
DPI-3290 [(+)-3-((α-R)-α-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-hydroxybenzyl)-N-(3-fluorophenyl)-N-methylbenzamide]. II. A Mixed Opioid Agonist with Potent Antinociceptive Activity and…
Allyl-2,5-dimethyl-1-piperazines have been of interest as analgesic agents for the management of moderate-to-severe pain. In this… 
1999
1999
Identification of cytochromes P450 involved in human liver microsomal metabolism of ecabapide, a prokinetic agent.
1. In vitro studies identified the hepatic cytochrome P450 (CYP) enzyme(s) involved in the major metabolism of ecabapide in human… 
1997
1997
An Unusual Trifluoromethyl Elimination Reaction from the 4,4-Bis(trifluoromethyl)-5-hydroxyimidazoline Ring System.
A facile detrifluoromethylation was observed when 4,4-bis(trifluoromethyl)-5-hydroxyimidazoline 5 was treated with a variety of… 
Review
1997
Review
1997
Pharmacology of the Gastric Pro‐kinetic Drug Ecabapide (DQ‐2511)
The pharmacology of ecabapide (DQ‐2511; 3‐[2‐(3,4‐dimethoxyphenyl)ethylcarbamoylmethyl]amino‐N‐methylbenzamide) is reviewed. 
1996
1996
A cyclic GMP‐dependent housekeeping Cl− channel in rabbit gastric parietal cells activated by a vasodilator ecabapide
1 The membrane potential of rabbit gastric parietal cells is dominated by a Cl− channel with a sub‐picosiemens single channel… 
1990
1990
Antiulcer effects of 3-[[[2-(3,4-dimethoxyphenyl)ethyl] carbamoyl]methyl]-amino-N-methylbenzamide in experimental gastric and duodenal ulcers.
Effects of 3-[[[2-(3,4-dimethoxyphenyl)ethyl]carbamoyl] methyl]-amino-N-methylbenzamide (DQ-2511), a newly synthesized compound… 
1983
1983
The formation and metabolism of N-hydroxymethyl compounds--III. The metabolic conversion of N-methyl and N,N,-dimethylbenzamides to N-hydroxymethyl compounds.
Highly Cited
1977
Highly Cited
1977
Thiohemiacetal formation by inhibitory aldehydes at the active site of papain.
Papain is strongly inhibited by aldehydes resembling carboxylic acids, released by hydrolysis of specific substrates (Westerik, J… 
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