Skip to search formSkip to main contentSkip to account menu

ebastine

Known as: 4-diphenylmethoxy-1-(3-(4-tert-butylbenzoyl)propyl)piperidine 
National Institutes of Health

Related topics

Related topics

6 relations

Broader (3)

ButyrophenonesHistamine H1 AntagonistsPiperidines

Narrower (2)

EbastelKestin
Kestine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
The effect of CYP2J2, CYP3A4, CYP3A5 and the MDR1 polymorphisms and gender on the urinary excretion of the metabolites of the H-receptor antihistamine ebastine: a pilot study.
AIMS To determine the effect of gender and the genetic polymorphisms of CYP2J2, CYP3A4, CYP3A5 and MDR1 on the urinary excretion… 
Highly Cited
2005
Highly Cited
2005
Identification and functional characterization of novel CYP2J2 variants: G312R variant causes loss of enzyme catalytic activity
CYP2J2 plays important roles in the metabolism of therapeutic drugs, such as astemizole and ebastine, as well as endogenous fatty… 
2001
2001
Effect of age and gender on the pharmacokinetics of ebastine after single and repeated dosing in healthy subjects.
OBJECTIVES Ebastine is a potent and selective H1-receptor antagonist indicated for allergic rhinitis which undergoes extensive… 
2001
2001
Effects of supratherapeutic doses of ebastine and terfenadine on the QT interval.
AIMS The objective of this study was to compare the effects of high doses of ebastine with terfenadine and placebo on QTc… 
2000
2000
The use of ebastine, a mast cell blocker, for treatment of oligozoospermia.
The effect of mast cell blocker (ebastine) on semen quality was evaluated in 15 idiopathic oligozoospermic males. Ten milligrams… 
Review
1999
Review
1999
Cardiac Effects of Ebastine and Other Antihistamines in Humans
The electrocardiographic effects of ebastine and its active metabolite, carebastine, have been studied alone and in relevant drug… 
1999
1999
Consistency and efficacy of cetirizine (10 mg) versus ebastine (20 mg) at 4 h on skin reactivity
AbstractObjective: We compared the consistency and efficacy of the two antihistamines, cetirizine (10 mg) and ebastine (20 mg) on… 
Review
1998
Review
1998
Antihistamines in severe/chronic rhinitis
Oral antihistamines generally represent the first line of treatment (after allergen avoidance) in mild seasonal allergic rhinitis… 
1996
1996
Microbial oxidation of ebastine
The microbial oxidation of ebastine to carebastine was investigated. Among the 15 micro-organisms examined, only… 
1994
1994
[Pharmacological study of ebastine, a novel histamine H1-receptor antagonist].
The anti-allergic activity of ebastine, a novel antihistamine, was assessed in comparison with several antihistamines. 1) Orally… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)