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doxorubicinone

National Institutes of Health

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adriamycin aglycone

Papers overview

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2020
2020
Intra-tumoral drug concentration mapping within solid tumor micro-milieu using in-vitro model and doxorubicin as a model drug
2008
2008
Optimization of a liquid chromatographic separation for the simultaneous determination of four anthracyclines and their respective 13-S-dihydro metabolites.
The optimization of a liquid chromatographic separation of four anthracyclines (doxorubicin, epirubicin, daunorubicin and… 
2004
2004
Subcellular metabolite profiles of the parent CCRF-CEM and the derived CEM/C2 cell lines after treatment with doxorubicin.
2004
2004
Comparative pharmacokinetics of escalating doses of doxorubicin in patients with metastatic breast cancer
SummaryRecombinant human granulocyte colony-stimulating factor (G-CSF) has been shown to reduce neutropenia following cytotoxic… 
2003
2003
Distribution of zeptomole-abundant doxorubicin metabolites in subcellular fractions by capillary electrophoresis with laser-induced fluorescence detection.
Doxorubicin (DOX) treatment of NS-1 mouse hybridoma cells results in the formation of zeptomole amounts of metabolites per cell… 
1995
1995
A sensitive procedure for the quantitation of free and N-(2-hydroxypropyl) methacrylamide polymer-bound doxorubicin (PK1) and some of its metabolites, 13-dihydrodoxorubicin, 13-dihydrodoxorubicinone…
Highly Cited
1993
Highly Cited
1993
A Sensitive and Simple High‐Performance Liquid Chromatographic Method for the Determination of Doxorubicin and Its Metabolites in Plasma
A sensitive high-performance liquid chromatographic (HPLC) method for the measurement of doxorubicin and its metabolites in… 
1989
1989
Doxorubicin toxicity and pharmacokinetics in old and young rats
1987
1987
Effect of doxorubicin on lipid peroxide levels in tissues of mice.
The tissue concentrations of doxorubicin (DOX, 15 mg/kg, ip) and daunorubicin (DAU, 15 mg/kg, ip) in mice were investigated to… 
1986
1986
Analysis of doxorubicin, 4'-epidoxorubicin, and their metabolites by liquid chromatography.
An analytical method based on isocratic HPLC separation and fluorescence detection was developed to allow for sensitive and… 
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