directed evolution
National Institutes of Health
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The formate dehydrogenase (FDH) from Candida boidinii is a well‐known enzyme in biocatalysis for NADH regeneration. Nevertheless…
An Fcab (Fc antigen binding) is a crystallizable fragment of IgG having C-terminal structural loops of CH3 domains engineered for…
Directed evolution has become a well-established tool for improving proteins and biological systems. A critical aspect of…
Fungal laccases are generalists biocatalysts with potential applications that range from bioremediation to novel green processes…
Disaccharide phosphorylases are interesting enzymes for the production of sugar phosphates from cheap starting materials and for…
We have engineered human epidermal growth factor (EGF) by directed evolution through yeast surface display for significantly…
G protein-coupled receptors (GPCRs) form a class of biological chemical sensors with an enormous diversity in ligand binding and…
Cofactor regeneration is an important solution to the problem of implementing complex cofactor requiring enzymatic reactions at…
Yeast display is a powerful tool for increasing the affinity and thermal stability of scFv antibodies through directed evolution…
Thermotoga neapolitana 1,4-β-d-glucan glucohydrolase A preferentially hydrolyzes cello-oligomers, such as cellotetraose…