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dihydrokainate

National Institutes of Health

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dihydrokainic acid

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2015
2015
POST ISCHEMIC ADMINISTRATION OF DIHYDROKAINATE, A GLT-1 BLOCKER FAILS TO ATTENUATE TRANSIENT FOCAL CEREBRAL ISCHEMIA EVOKED NEURODEGENERATION IN RATS
Recently modulation of the GLT-1 transporter has been extensively focussed in various models of ischemic injury for evaluating… 
2014
2014
The effects of the β-lactam antibiotic, ceftriaxone, on forepaw stepping and l-DOPA-induced dyskinesia in a rodent model of Parkinson’s disease
Glutamate receptor antagonists can improve the symptoms of Parkinson’s disease (PD) and reduce l-3,4-dihydroxyphenylalanine (l… 
2013
2013
Ceftriaxone attenuates the clinical EAE course in mice in the presence of the EAAT2 transport inhibitor dihydrokainate.
2007
2007
The Effect of Dihydrokainate on the Pyramidal Neurons in the CA1 Hippocampus
Objective The effect of DHK, a selective inhibitor of glutamate transporter subtype GLT-1,on the pyramidal neurons in the CA1… 
2007
2007
Effect of dihydrokainate, a selective inhibitor of glutamate transporter subtype GLT-1, on the protection of cerebral ischemic preconditioning in rats
AIM: To investigate the effect of dihydrokainate (DHK) on brain ischemic tolerance (BIT) induced by cerebral ischemic… 
2007
2007
An investigation of the neurochemical mechanisms underlying the contrasting effects of d-amphetamine in two subregions of the rat anterior cingulate cortex
d-Amphetamine inhibits neuronal uptake, and causes impulse-independent release of monoamines. There are several reports that d… 
2004
2004
Dissociation of [H]L-Glutamate Uptake from L-Glutamate- Induced [H]D-Aspartate release by 3-Hydroxy-4,5,6,6a- tetrahydro-3aH-pyrrolo[3,4-d]isoxazole-4-carboxylic Acid and 3-Hydroxy-4,5,6,6a…
We characterized the interaction of two conformationally constrained aspartate and glutamate analogs, 3-hydroxy-4,5,6… 
Review
1998
Review
1998
cloning led to the isolation of cDNAs for three glutamate transporter subtypes in nonhuman systems : GLAST
Sodium-dependent transport into astrocytes is critical for maintaining the extracellular concentrations of glutamate below toxic…