dihydroceramide

Known as: C2-dihydroceramide, N-acetylsphinganine, dihydro-ceramide 
 
National Institutes of Health

Papers overview

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2011
2011
The dihydroceramide desaturase (DES) enzyme is responsible for inserting the 4,5-trans-double bond to the sphingolipid backbone… (More)
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Highly Cited
2009
Highly Cited
2009
Resveratrol has both apoptosis and autophagy-promoting activities in different cancer cells. Dihydroceramide is the immediate… (More)
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2006
Highly Cited
2006
Early in apoptosis, ceramide levels rise and the mitochondrial outer membrane becomes permeable to small proteins. The self… (More)
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2005
2005
We demonstrated recently (Riebeling, C., Allegood, J.C., Wang, E., Merrill, A. H. Jr., and Futerman, A. H. (2003) J. Biol. Chem… (More)
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2003
Highly Cited
2003
Overexpression of upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance… (More)
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1997
Highly Cited
1997
Ceramide (N-acylsphingosine) biosynthesis has been proposed to involve introduction of the 4,5-trans-double bond of sphingosine… (More)
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1997
Highly Cited
1997
Ceramide is a sphingolipid that is generated in the signaling of inflammatory cytokines such as tumor necrosis factor (TNF… (More)
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1997
1997
Ceramide has been suggested to be a potent bioactive lipid involved in cell growth, differentiation and apoptosis. Its precursor… (More)
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Highly Cited
1993
Highly Cited
1993
Ceramide is emerging as a putative second messenger mediating effects of extracellular agents on cell growth and differentiation… (More)
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1993
Highly Cited
1993
Sphingomyelin hydrolysis and ceramide generation have been implicated in a signal transduction pathway that mediates the effects… (More)
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