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dihydroartemisinin
Known as:
dihydroartemisinine
, dihydroquinghaosu
, quinghaosu, dihydro-
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National Institutes of Health
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Related topics
Related topics
3 relations
Broader (2)
Antimalarials
Artemisinins
artenimol
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Heme synthesis increases artemisinin-induced radical formation and cytotoxicity that can be suppressed by superoxide scavengers.
Shiming Zhang
,
Hui Chen
,
G. Gerhard
Chemico-Biological Interactions
2010
Corpus ID: 32158978
Highly Cited
2008
Highly Cited
2008
Antimalarial artesunate protects sepsis model mice against heat-killed Escherichia coli challenge by decreasing TLR4, TLR9 mRNA expressions and transcription factor NF-kappa B activation.
Bin Li
,
Rong Zhang
,
+10 authors
Hong Zhou
International Immunopharmacology
2008
Corpus ID: 31968673
Highly Cited
2008
Highly Cited
2008
Direct quantitation of active ingredients in solid artesunate antimalarials by noncovalent complex forming reactive desorption electrospray ionization mass spectrometry
Leonard Nyadong
,
S. Late
,
M. Green
,
A. Banga
,
F. Fernández
Journal of the American Society for Mass…
2008
Corpus ID: 205702133
Highly Cited
1999
Highly Cited
1999
Multiple dose pharmacokinetics of artemether in Chinese patients with uncomplicated falciparum malaria.
M. V. van Agtmael
,
S. Cheng-qi
,
J. Qing
,
R. Mull
,
C. van Boxtel
International Journal of Antimicrobial Agents
1999
Corpus ID: 780851
Review
1998
Review
1998
Neurotoxicity and artemisinin compounds do the observations in animals justify limitation of clinical use?
A. Dayan
Medecine tropicale : revue du Corps de sante…
1998
Corpus ID: 24275060
High parenteral doses of certain artemisinin derivatives can produce a limited and unique, selective brain stem neuronopathy in…
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Highly Cited
1995
Highly Cited
1995
Antimalarial activity of new dihydroartemisinin derivatives. 6. alpha-Alkylbenzylic ethers.
A. Lin
,
Robert E. Miller
Journal of Medicinal Chemistry
1995
Corpus ID: 23996297
A series of diastereomeric dihydroartemisinin alpha-alkylbenzylic ethers was synthesized in search for analogs with higher…
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Highly Cited
1991
Highly Cited
1991
Determination of the antimalarial arteether and its deethylated metabolite dihydroartemisinin in plasma by high-performance liquid chromatography with reductive electrochemical detection.
V. Meléndez
,
J. Peggins
,
T. Brewer
,
A. Theoharides
Journal of Pharmacy and Science
1991
Corpus ID: 31384489
A rapid, sensitive, and specific reversed-phase HPLC method using reductive electrochemical detection has been developed for the…
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1990
1990
In vitro activity of artemisinin, its derivatives, and pyronaridine against different strains of Plasmodium falciparum.
M. Alin
,
A. Björkman
,
M. Ashton
Transactions of the Royal Society of Tropical…
1990
Corpus ID: 38629820
1983
1983
Effects of qinghaosu and related compounds on incorporation of [G-3H] hypoxanthine by Plasmodium falciparum in vitro.
Z. L. Li
,
H. Gu
,
D. Warhurst
,
W. Peters
Transactions of the Royal Society of Tropical…
1983
Corpus ID: 9415818
1965
1965
Analogs of tetrahydrofolic acid. XXVII. Hydrophobic bonding to dihydrofolic reductase by 2-amino-4,6-disubstituted-5-alkylpyrimidines and 1-alkyl-4,6-diamino-1,2-dihydro-s-triazines.
B. R. Baker
,
H. O. Beng-Thong
,
D. Santi
Journal of Pharmacy and Science
1965
Corpus ID: 19448917
Strong hydrophobic bonding to dihydrofolic reductase has been observed by alkyl groups attached to the 5-position of pyrimidines…
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