diacetolol

Known as: RS-1-(4-acetamido-2-acetylphenoxy)-2-hydroxy-3-isopropylaminopropane hydrochloride, acetamide, N-(3-acetyl-4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)phenyl)-, (+-)-, acetyl acebutolol 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1980-2015
024619802015

Papers overview

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2004
2004
A liquid chromatographic-mass spectrometric assay with atmospheric pressure chemical ionization (LC-APCI-MS) is presented for… (More)
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2003
2003
Acebutolol (AC) is a chiral beta-adrenergic receptor-blocking agent, which has been shown to be clinically effective in… (More)
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1999
1999
A stereoselective direct liquid chromatographic method for assay of the enantiomers of the beta-adrenergic blocker acebutolol (AC… (More)
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1997
1997
Acebutolol (AC) is a chiral beta-blocker which is extensively metabolized to an active, chiral metabolite, diacetolol (DC… (More)
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1985
1985
The pharmacokinetics of acebutolol and its major metabolite, diacetolol, following a single 400 mg oral dose, were investigated… (More)
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1982
1982
Diacetolol (M & B 16,942), the major metabolite of the beta-adrenoceptor blocking agent, has been compared pharmacologically with… (More)
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1982
1982
The beta-blocking action of diacetolol was studied in six healthy subjects after oral administration of placebo, 200, 400, and… (More)
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1981
1981
1 The pharmacological effects and plasma levels of diacetolol, the major human metabolite of acebutolol, were measured in a… (More)
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1981
1981
The pharmacokinetics and bioavailability of diacetolol, the principal metabolite of acebutolol, were studied in 6 healthy… (More)
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1980
1980
1 Acebutolol or diacetolol were added to fresh human plasma in varying concentrations and their extent of binding at 25 degrees C… (More)
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