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diacetolol

Known as: RS-1-(4-acetamido-2-acetylphenoxy)-2-hydroxy-3-isopropylaminopropane hydrochloride, acetamide, N-(3-acetyl-4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)phenyl)-, (+-)-, acetyl acebutolol 
National Institutes of Health

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Acebutolol
analogs & derivatives

Papers overview

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2008
2008
Circadian Changes in the Pharmacokinetics of Acebutolol Orally Administered to Rabbits
Circadian variations of acebutolol and its main metabolite, diacetolol pharmacokinetics were studied after a single oral… 
2001
2001
Pharmacokinetics of Acebutolol and Diacetolol After Oral Administration of Acebutolol in Rabbits with Folate-Induced Renal Failure
Acebutolol (ABT) is almost absorbed after oral administration, but its bioavailability is reduced because of considerable first… 
1993
1993
The Clearance of Free Forms of Propranolol, Acebutolol and Its Metabolite Diacetolol from Plasma and Hemolyzed Whole Blood
1991
1991
[Acebutolol and diacetolol: their binding to plasma proteins and erythrocytes and secretion with the saliva].
Thirty-two patients with hypertensive disease were treated with a cardioselective blocker of beta-adrenergic receptors acebutolol… 
1991
1991
[Acebutolol and diacetolol: their binding to plasma proteins and erythrocytes and secretion with the saliva].
Thirty-two patients with hypertensive disease were treated with a cardioselective blocker of beta-adrenergic receptors acebutolol… 
1985
1985
Acebutolol and oral surgery: plasma levels following a single oral dose.
Twenty eight patients were randomly allocated into treatment or placebo groups. The treatment group received a single 400 mg oral… 
1983
1983
A pharmacokinetic study of acebutolol in aged subjects as compared to young subjects.
Pharmacokinetics of acebutolol have been studied in hypertensive aged patients (79.4 +/- 3.8 years) and in young healthy subjects… 
1982
1982
The beta-blocking effect of diacetolol in humans and its relationship to plasma levels.
The beta-blocking action of diacetolol was studied in six healthy subjects after oral administration of placebo, 200, 400, and… 
1982
1982
The influence of renal function on plasma levels and urinary excretion of acebutolol and its main N-acetyl metabolite.
The pharmacokinetics of acebutolol and its major N-acetyl metabolite diacetolol were determined following acute intravenous and… 
1981
1981
The penetration of acebutolol and its major metabolite, diacetolol, into human cerebrospinal fluid and saliva.
Acebutolol is a cardioselective /8-adrenoceptor blocking drug and has a major metabolite, diacetolol (Meffin, Harapat & Harrison…