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diacetolol

Known as: RS-1-(4-acetamido-2-acetylphenoxy)-2-hydroxy-3-isopropylaminopropane hydrochloride, acetamide, N-(3-acetyl-4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)phenyl)-, (+-)-, acetyl acebutolol 
National Institutes of Health

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Broader (1)

Acebutolol
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
Effects of grapefruit juice on the pharmacokinetics of acebutolol.
AIMS We aimed to investigate effects of grapefruit juice on acebutolol pharmacokinetics. METHODS In a randomized cross-over… 
Highly Cited
2004
Highly Cited
2004
Simultaneous determination of thirteen beta-blockers and one metabolite by gradient high-performance liquid chromatography with photodiode-array UV detection.
Highly Cited
2004
Highly Cited
2004
Screening for library-assisted identification and fully validated quantification of 22 beta-blockers in blood plasma by liquid chromatography-mass spectrometry with atmospheric pressure chemical…
1999
1999
Enantioselective high performance liquid chromatographic assay of acebutolol and its active metabolite diacetolol in human serum.
A stereoselective direct liquid chromatographic method for assay of the enantiomers of the beta-adrenergic blocker acebutolol (AC… 
Review
1990
Review
1990
Pharmacokinetics of beta-adrenoceptor blocking agents: clinical significance of hepatic and/or renal clearance.
A great number of beta-adrenoceptor blocking drugs are now available for clinical use which show great differences with respect… 
1990
1990
Comparative beta-adrenoceptor blocking effects of propranolol, bisoprolol, atenolol, acebutolol and diacetolol on the human isolated bronchus.
Five beta-adrenoceptor blockers, propranolol, acebutolol, diacebutolol, atenolol and bisoprolol, were tested for their… 
Review
1985
Review
1985
Acebutolol: ten years of experience.
1984
1984
Preliminary study of the disposition in man of acebutolol and its metabolite, diacetolol, using a new stereoselective hplc method
A new stereospecific hplc method that is capable of simultaneously quantitating the S‐(‐)‐ and R−(+)−enantiomers of acebutolol… 
1981
1981
Observations on the clinical pharmacology and plasma concentrations of diacetolol, the major human metabolite of acebutolol.
1 The pharmacological effects and plasma levels of diacetolol, the major human metabolite of acebutolol, were measured in a… 
1980
1980
Blood plasma binding of acebutolol and diacetolol in man.
1 Acebutolol or diacetolol were added to fresh human plasma in varying concentrations and their extent of binding at 25 degrees C… 
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