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diacetolol
Known as:
RS-1-(4-acetamido-2-acetylphenoxy)-2-hydroxy-3-isopropylaminopropane hydrochloride
, acetamide, N-(3-acetyl-4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)phenyl)-, (+-)-
, acetyl acebutolol
National Institutes of Health
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Broader (1)
Acebutolol
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
1985
Review
1985
Acebutolol: ten years of experience.
George De Bono
,
C. Kaye
,
E. Roland
,
A. Summers
American Heart Journal
1985
Corpus ID: 260850327
1985
1985
Lack of effect of liver disease on the pharmacokinetics of acebutolol and diacetolol: a single dose study.
R. Zaman
,
D. Jack
,
M. Wilkins
,
M. Kendall
Biopharmaceutics & drug disposition
1985
Corpus ID: 33754485
The pharmacokinetics of acebutolol and its major metabolite, diacetolol, following a single 400 mg oral dose, were investigated…
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1985
1985
In vitro studies on the pharmacological properties of diacetolol, the major metabolite of acebutolol in man.
U. Borchard
,
D. Hafner
,
C. Hirth
Archives internationales de pharmacodynamie et de…
1985
Corpus ID: 37644946
The cardioselectivity and specificity of diacetolol, the major metabolite of the beta-adrenoceptor blocking drug acebutolol, was…
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1985
1985
Pharmacologic properties of acebutolol: relationship of hydrophilicity to central nervous system penetration.
D. Abernethy
,
R. Arendt
,
D. Greenblatt
American Heart Journal
1985
Corpus ID: 38442741
1985
1985
Clinical pharmacology of acebutolol.
J. Ryan
American Heart Journal
1985
Corpus ID: 24541027
1984
1984
Preliminary study of the disposition in man of acebutolol and its metabolite, diacetolol, using a new stereoselective hplc method
M. Sankey
,
A. Gulaid
,
C. Kaye
The Journal of pharmacy and pharmacology
1984
Corpus ID: 9175032
A new stereospecific hplc method that is capable of simultaneously quantitating the S‐(‐)‐ and R−(+)−enantiomers of acebutolol…
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1981
1981
Observations on the clinical pharmacology and plasma concentrations of diacetolol, the major human metabolite of acebutolol.
K. Ohashi
,
S. Warrington
,
+4 authors
P. Turner
British Journal of Clinical Pharmacology
1981
Corpus ID: 41162319
1 The pharmacological effects and plasma levels of diacetolol, the major human metabolite of acebutolol, were measured in a…
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1981
1981
The penetration of acebutolol and its major metabolite, diacetolol, into human cerebrospinal fluid and saliva.
R. Zaman
,
D. Jack
,
M. Kendall
British Journal of Clinical Pharmacology
1981
Corpus ID: 41732040
Acebutolol is a cardioselective /8-adrenoceptor blocking drug and has a major metabolite, diacetolol (Meffin, Harapat & Harrison…
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1981
1981
Pharmacokinetics and bioavailability of diacetolol, the main metabolite of acebutolol
B. Flouvat
,
A. Roux
,
+4 authors
J. Gregoire
European Journal of Clinical Pharmacology
1981
Corpus ID: 20354753
SummaryThe pharmacokinetics and bioavailability of diacetolol, the principal metabolite of acebutolol, were studied in 6 healthy…
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1980
1980
Blood plasma binding of acebutolol and diacetolol in man.
T. Coombs
,
C. J. Coulson
,
V. J. Smith
British Journal of Clinical Pharmacology
1980
Corpus ID: 24612287
1 Acebutolol or diacetolol were added to fresh human plasma in varying concentrations and their extent of binding at 25 degrees C…
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