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diacetolol

Known as: RS-1-(4-acetamido-2-acetylphenoxy)-2-hydroxy-3-isopropylaminopropane hydrochloride, acetamide, N-(3-acetyl-4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)phenyl)-, (+-)-, acetyl acebutolol 
 
National Institutes of Health

Papers overview

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2009
2009
A high through-put, sensitive, and enantioselective LC-MS/MS-based bioanalytical method was developed and validated for the… Expand
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2005
2005
AIMS We aimed to investigate effects of grapefruit juice on acebutolol pharmacokinetics. METHODS In a randomized cross-over… Expand
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Highly Cited
2004
Highly Cited
2004
A new rapid and sensitive high-performance liquid chromatography (HPLC) method has been developed for the simultaneous… Expand
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Highly Cited
2004
Highly Cited
2004
A liquid chromatographic-mass spectrometric assay with atmospheric pressure chemical ionization (LC-APCI-MS) is presented for… Expand
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2004
2004
SummaryThe pharmacokinetics and bioavailability of diacetolol, the principal metabolite of acebutolol, were studied in 6 healthy… Expand
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  • table 1
  • table 2
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2003
2003
Acebutolol (AC) is a chiral beta-adrenergic receptor-blocking agent, which has been shown to be clinically effective in… Expand
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2000
2000
OBJECTIVES The multidrug transporter P-glycoprotein (P-gp) appears to play a significant role in drug absorption and disposition… Expand
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1999
1999
A stereoselective direct liquid chromatographic method for assay of the enantiomers of the beta-adrenergic blocker acebutolol (AC… Expand
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Review
1990
Review
1990
  • U. Borchard
  • Clinical physiology and biochemistry
  • 1990
  • Corpus ID: 27296637
A great number of beta-adrenoceptor blocking drugs are now available for clinical use which show great differences with respect… Expand
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1982
1982
Diacetolol (M & B 16,942), the major metabolite of the beta-adrenoceptor blocking agent, has been compared pharmacologically with… Expand
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