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Acebutolol

Known as: Acebutolol [Chemical/Ingredient], (±)-acebutolol, N-[3-Acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]butanamide 
A synthetic butyranilide derivative with hypotensive and antiarrhythmic activity. Acebutolol acts as a cardioselective beta-adrenergic antagonist… 
National Institutes of Health

Related topics

Related topics

39 relations
Acebutolol / HydrochlorothiazideAcebutolol Hydrochloride 200 MG Oral Capsule [Sectral]Acebutolol:MCnc:Pt:XXX:QnAcebutolol:MRat:24H:Urine:Qn

Narrower (8)

Acebutolol HydrochlorideM&B-17803 ANeptalPrent

Broader (4)

Adrenergic beta-1 Receptor AntagonistsAnti-Arrhythmia AgentsAntihypertensive AgentsSympathomimetics

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2002
2002
Propranolol and metoprolol enhance the anticonvulsant action of valproate and diazepam against maximal electroshock
Highly Cited
2001
Highly Cited
2001
Quantitative structure-retention and retention-activity relationships of beta-blocking agents by micellar liquid chromatography.
Highly Cited
2000
Highly Cited
2000
Comparative LC-MS and HPLC analyses of selected antiepileptics and beta-blocking drugs.
Highly Cited
1996
Highly Cited
1996
Acebutolol Overdose Treated with Hemodialysis and Extracorporeal Membrane Oxygenation
A case involving a 27‐year‐old woman who ingested an overdose of acebutolol is presented. Extracorporeal membrane oxygenation was… 
1981
1981
Preliminary observations on the excretion of acebutolol and its acetyl metabolite in the urine and faeces of man
synergism between the actions of diethylcarbamazine Whereas the inhibition of immunological release of and isoprenaline similar… 
Review
1980
Review
1980
Hemodynamic effects of newer antiarrhythmic drugs.
1979
1979
Development of antinuclear antibodies during acebutolol therapy
Eleven patients were studied while taking the beta blocker acebutolol for a period ranging from 12 to more than 24 wk. Control… 
Highly Cited
1978
Highly Cited
1978
Blockade of isoprenaline-induced changes in plasma free fatty acids, immunoreactive insulin levels and plasma renin activity in healthy human subjects, by propranolol, pindolol, practolol, atenolol…
Abstract 1 The effects of intravenously administered propranolol 0.01 and 0.03, pindolol 0.001 and 0.003, practolol 0.12 and 0… 
1977
1977
Acebutolol disposition after intravenous administration
The disposition of acebutolol has been studied following intravenous doses of 0.25 to 1.0 mg/kg in 9 healthy subjects using a… 
1975
1975
Plasma levels and beta-adrenoceptor blockade with acebutolol, practolol and propranolol in man.
1 The degree of beta-adrenoceptor blockade of isoprenaline-induced tachycardia has been determined in three healthy volunteers… 
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