Acebutolol

Known as: Acebutolol [Chemical/Ingredient], (±)-acebutolol, N-[3-Acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]butanamide

A synthetic butyranilide derivative with hypotensive and antiarrhythmic activity. Acebutolol acts as a cardioselective beta-adrenergic antagonist…

National Institutes of Health

Papers overview

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1983

A case of a nonfatal acebutolol intoxication in a 15 year old female is described. Ingestion of 7600 mg acebutolol resulted in a…

1983

Massive overdosage of adrenergic blocking drugs is associated with severe morbidity and a high mortality rate. We report the case…

1981

synergism between the actions of diethylcarbamazine Whereas the inhibition of immunological release of and isoprenaline similar…

1979

Eleven patients were studied while taking the beta blocker acebutolol for a period ranging from 12 to more than 24 wk. Control…

1979

The relative cardioselectivity of acebutolol in man was studied by comparing its hemodynamic effects with those of two other…

1979

Eleven patients with essential hypertension were treated with the beta adrenergic blocker, acebutolol. Clinical, systemic, and…

1978

1. Eleven hypertensive patients were studied in a double-blind comparison of acebutolol, a beta-adrenoceptor blocker, and placebo…

1976

Using a balanced, randomized, crossover design, single intravenous (1 mg/kg) or oral (3 X 100 mg) doses of acebutolol were…

1976

1 The effects of acebutolol, practolol and propranolol (0.5‐3 mm) on calcium uptake, calcium binding and ATPase activities of the…

1975

1 The degree of beta-adrenoceptor blockade of isoprenaline-induced tachycardia has been determined in three healthy volunteers…