desmethylmianserin

A gas chromatographic–mass spectrometric (GC–MS) method in positive ion chemical ionization mode in combination with a solid… Expand

A gas chromatographic-mass spectrometric method (GC-MS) for the simultaneous determination of the 'new' antidepressants… Expand

Antidepressants belong to a variety of chemical and pharmacologic classes. Most require therapeutic drug monitoring, at least in… Expand

The stability of 46 drugs in postmortem femoral blood stored for one year at -20 degrees C was investigated. The drugs included… Expand

Steady state concentrations of (S)- and (R)-mianserin and desmethylmianserin were measured in 21 homozygous extensive… Expand

The antidepressant mianserin is administered as a racemate of the S(+)- and R(-)-enantiomers. Previous in-vitro studies have… Expand

An HPLC method is presented which allows the measurement in the same run of the enantiomers of mianserin, desmethylmianserin, and… Expand

1. The cytotoxicity of metabolites generated from phenytoin, sorbinil and mianserin by human and mouse liver microsomes was… Expand

ABSTRACT ‐ S(+)‐mianserin is the more potent enantiomer of mianserin in pharmacological tests indicative for antidepressant… Expand

1 S(+)-mianserin is the more potent enantiomer of mianserin in pharmacological tests indicative for antidepressant activity… Expand