FAQ

desmethylmianserin

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1981-2008
012319812008

Related topics

Related topics

2 relations

Broader (1)

Mianserin

Narrower (1)

Org OH 46

Related mentions per year

Related mentions per year

1971-2018
197019801990200020102020
desmethylmianserin
Mianserin
Org OH 46

Papers overview

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2007
2007
Comparison of electron and chemical ionization modes by validation of a quantitative gas chromatographic-mass spectrometric assay of new generation antidepressants and their active metabolites in…
A gas chromatographic-mass spectrometric method (GC-MS) for the simultaneous determination of the 'new' antidepressants… (More)
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2006
2006
A fully automated turbulent-flow liquid chromatography-tandem mass spectrometry technique for monitoring antidepressants in human serum.
Antidepressants belong to a variety of chemical and pharmacologic classes. Most require therapeutic drug monitoring, at least in… (More)
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2004
2004
Stability of drugs in stored postmortem femoral blood and vitreous humor.
The stability of 46 drugs in postmortem femoral blood stored for one year at -20 degrees C was investigated. The drugs included… (More)
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1998
1998
Steady state concentrations of the enantiomers of mianserin and desmethylmianserin in poor and in homozygous and heterozygous extensive metabolizers of debrisoquine.
Steady state concentrations of (S)- and (R)-mianserin and desmethylmianserin were measured in 21 homozygous extensive… (More)
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1997
1997
Effects of thioridazine, an inhibitor of CYP2D6, on the steady-state plasma concentrations of the enantiomers of mianserin and its active metabolite, desmethylmianserin, in depressed Japanese…
The antidepressant mianserin is administered as a racemate of the S(+)- and R(-)-enantiomers. Previous in-vitro studies have… (More)
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1994
1994
Stereoselective disposition of mianserin is related to debrisoquin hydroxylation polymorphism.
The pharmacokinetics of mianserin and its main metabolite desmethylmianserin were studied in poor and extensive metabolizers of… (More)
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1994
1994
Determination of the enantiomers of mianserin, desmethylmianserin, and 8-hydroxymianserin in the plasma and urine of mianserin-treated patients.
An HPLC method is presented which allows the measurement in the same run of the enantiomers of mianserin, desmethylmianserin, and… (More)
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1993
1993
Steady-state plasma concentrations of mianserin and its major active metabolite, desmethylmianserin.
The steady-state plasma concentrations of mianserin and its major active metabolite, desmethylmianserin, were measured in 76… (More)
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1992
1992
Subjective side effects of mianserin in relation to plasma concentrations of mianserin and desmethylmianserin.
The main purpose of the present study was to examine the possibility that plasma concentrations of mianserin and its metabolite… (More)
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1983
1983
The potential therapeutic role of the enantiomers and metabolites of mianserin.
1 S(+)-mianserin is the more potent enantiomer of mianserin in pharmacological tests indicative for antidepressant activity… (More)
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