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demecarium bromide

Known as: Visumiotic, demecarium bromide [Chemical/Ingredient], demecastigmine 
The bromide salt form of demecarium, a quaternary ammonium compound and a long-acting cholinesterase inhibitor with parasympathomimetic activity… 
National Institutes of Health

Related topics

Related topics

7 relations

Broader (2)

Ammonium CompoundsDemecarium
Angle Closure GlaucomaDrug AllergyPoisoning by parasympathomimetics (cholinergics)Retinal Detachment

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2000
Highly Cited
2000
The efficacy of topical prophylactic antiglaucoma therapy in primary closed angle glaucoma in dogs: a multicenter clinical trial.
The ability of either 0.5% betaxolol (1 drop topically, bid; n=31) or a combination of 0.25% demecarium bromide and a topical… 
1994
1994
Effect of topically applied 2% pilocarpine and 0.25% demecarium bromide on blood-aqueous barrier permeability in dogs.
The effect of topically applied 2% pilocarpine and 0.25% demecarium bromide on aqueous humor flare was evaluated while treating… 
1993
1993
Effect of topically applied demecarium bromide and echothiophate iodide on intraocular pressure and pupil size in beagles with normotensive eyes and beagles with inherited glaucoma.
Topically applied demecarium bromide (0.125 and 0.25%) and echothiophate iodide (0.125 and 0.25%) solutions were evaluated in… 
Review
1990
Review
1990
Glaucoma in the dog and cat.
1970
1970
Cellular uptake of some amino acids and amines in vitro into rabbit and monkey anterior eye segment preparations.
Review
1968
Review
1968
Experimental miotic cataract. I. Effects of miotics on lens structure, cation content, and hydration.
Clinical surveys suggest that miotics produce lens opacities. Since such studies examine the diseased eyes of an older age group… 
1968
1968
Experimental miotic cataract. II. Permeability, cation transport, and intermediary metabolism.
The present study investigates the mechanism underlying the alterations in sodium, potassium, and water content brought about by… 
1964
1964
THE CONSTRICTOR ACTION FOR VARIOUS ANTI-GLAUCOMA DRUGS ON THE IRIS ARTERY OF THE CAT.
1960
1960
Demecarium bromide and echothiophate iodide in chronic glaucoma.
Demecarium bromide (BC-48 or Humorsol) and echothiophate (Phospholine) iodide are potent long acting inhibitors of cholinesterase… 
1959
1959
Effect of demecarium bromide (BC 48) on intraocular pressure in man.
It is now widely held that the treatment of chronic simple glaucoma should be conservative, because it is realized that the… 
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