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Demecarium

Known as: N,N'-Bis(3-Trimethylammoniumphenoxycarbonyl)-N,N'-Dimethyldecamethylenediamine, 3,3'-(1,10-Decanediylbis((Methylimino)Carbonyloxy))Bis(N,N,N-Trimethylbenzenaminium), (M-Hydroxyphenyl)Trimethylammonium Decamethylenebis(Methylcarbamate) 
A quaternary ammonium compound that serves as a long-acting cholinesterase inhibitor with parasympathomimetic activity. When used topically… 
National Institutes of Health

Related topics

Related topics

9 relations
Angle Closure GlaucomaDrug AllergyPoisoning by parasympathomimetics (cholinergics)Retinal Detachment

Broader (2)

Cholinesterase InhibitorsQuaternary Ammonium Compounds

Narrower (2)

Tosmilendemecarium bromide

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Crystal structure of a new molecular salt: 4-aminobenzenaminium 5-carboxypentanoate
The asymmetric unit of the title molecular salt, consists of half a 4-aminobenzenaminium cation and a half a 5-carboxypentanoate… 
2017
2017
Glaucoma Isoflurophate Demecarium Myasthenia Gravis Physostigmine Ambenonium Neostigmine Pyridostigmine Pralidoxime Tubocurarine ACHE Tacrine Choline Rivastigmine Donepezil Galantamine
Drug discovery is a lengthy, expensive and difficult process. Indentifying and understanding the hidden relationships among drugs… 
2005
2005
The accumulation of alpha aminoisobutyric acid by rabbit ciliary body-iris preparations
H.-labeled alpha aminoisobutyric acid (AIB) was accumulated against a concentration gradient by rabbit ciliary body-iris… 
1982
1982
Drug‐Induced Cicatrizing Conjunctivitis Simulating Ocular Pemphigoid
We describe two cases of presumed drug-induced cicatrizing conjunctivitis simulating ocular pemphigoid following pilocarpine… 
1982
1982
Activation and blockade of cardiac muscarinic receptors by endogenous acetylcholine and cholinesterase inhibitors.
Cholinesterase inhibitors are known to potentiate the effects of acetylcholine (ACh) and vagal stimulation on the myocardium. The… 
1978
1978
Agents anticholinestérasiques et tératogénèse axiale chez l'embryon de Caille
  • R. Meiniel
  • Wilhelm Roux's archives of developmental biology
  • 1978
  • Corpus ID: 21000478
SummaryThe results of an investigation made with organo-phosphorous compounds (OP), carbamates (C), and a compound including… 
1970
1970
Antiglaucoma drug effects on corneal epithelium. A comparative study in tissue culture.
Rabbit and human corneal epithelium was studied in tissue cultures for the effects of a variety of topically administered… 
1970
1970
The effects of decapsulation on ion movements across the lens of the toad, Bufo marinus. Influence on drug actions.
The lens of the toad Bufo marinus, like that of mammals, slowly gains Na and loses K when incubated in vitro. This process is… 
1964
1964
INHIBITION OF MONAMINE OXIDASE BY AN ANTICHOLINESTERASE (DEMECARIUM BROMIDE).
1964
1964
Role of the polymethylene chain in derivatives of demecarium bromide on the inhibition of monoamine oxidase
& Conti, 1964). The results obtained with some selected compounds-reported in Table 1-show the following: (1) The presence of the… 
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