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delta(12)-prostaglandin J(2)

Known as: delta12-PGJ2 
National Institutes of Health

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Broader (1)

Prostaglandin D2

Papers overview

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Highly Cited
2010
Highly Cited
2010
Alkylation of the Tumor Suppressor PTEN Activates Akt and β-Catenin Signaling: A Mechanism Linking Inflammation and Oxidative Stress with Cancer
PTEN, a phosphoinositide-3-phosphatase, serves dual roles as a tumor suppressor and regulator of cellular anabolic/catabolic… 
Highly Cited
2008
Highly Cited
2008
Macrophage Secretory Phospholipase A2 Group X Enhances Anti-inflammatory Responses, Promotes Lipid Accumulation, and Contributes to Aberrant Lung Pathology*
Secreted phospholipase A2 group X (sPLA2-X) is one of the most potent enzymes of the phospholipase A2 lipolytic enzyme… 
Highly Cited
2004
Highly Cited
2004
Delta12-Prostaglandin J2 inhibits the ubiquitin hydrolase UCH-L1 and elicits ubiquitin-protein aggregation without proteasome inhibition.
Highly Cited
2004
Highly Cited
2004
Glutathione S-transferases (GSTs) inhibit transcriptional activation by the peroxisomal proliferator-activated receptor gamma (PPAR gamma) ligand, 15-deoxy-delta 12,14prostaglandin J2 (15-d-PGJ2).
15-Deoxy-Delta(12,14)prostaglandin J(2) (15-d-PGJ(2)), a terminal metabolite of the J-series cyclopentenone prostaglandins… 
Review
2002
Review
2002
Lipocalin-type and hematopoietic prostaglandin D synthases as a novel example of functional convergence.
2002
2002
Effect of prostaglandin-J(2) on VEGF synthesis depends on the induction of heme oxygenase-1.
Heme oxygenase-1 (HO-1) is an inducible enzyme that degrades heme to carbon monoxide, iron ions, and biliverdin. Its expression… 
Highly Cited
2000
Highly Cited
2000
Ligand type-specific Interactions of Peroxisome Proliferator-activated Receptor γ with Transcriptional Coactivators*
The nuclear peroxisome proliferator-activated receptor γ (PPARγ) is a member of the nuclear receptor superfamily and acts as a… 
Highly Cited
1999
Highly Cited
1999
Influence of J series prostaglandins on apoptosis and tumorigenesis of breast cancer cells.
This study was undertaken to investigate the influence of the peroxisome proliferator-activated receptor gamma (PPARgamma… 
1999
1999
Prostaglandin J2 and its metabolites promote neurite outgrowth induced by nerve growth factor in PC12 cells.
Although A- and J-type prostaglandins (PG's) arrest the cell cycle at the G1 phase in vitro and suppress tumor growth in vivo… 
Highly Cited
1998
Highly Cited
1998
Characterization of the recombinant human prostanoid DP receptor and identification of L‐644,698, a novel selective DP agonist
A human embryonic kidney cell line [HEK 293(EBNA)] stably expressing the human recombinant prostaglandin D2 (PGD2) receptor (hDP… 
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