Prostaglandin D2

Known as: D2, Prostaglandin, F2 alpha, 11-Dehydroprostaglandin, PGD2 
The principal cyclooxygenase metabolite of arachidonic acid. It is released upon activation of mast cells and is also synthesized by alveolar… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1974-2018
05010019742018

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
BACKGROUND Activation of the group 2 innate lymphoid cell (ILC2) population leads to production of the classical type 2 cytokines… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Nicotinic acid, used for atherosclerosis treatment, has an adverse effect of skin flushing. The flushing mechanism, thought to be… (More)
Is this relevant?
Highly Cited
2005
Highly Cited
2005
During mammalian gonadal development, nuclear import/export of the transcription factor SOX9 is a critical step of the Sry… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Prostaglandin D(2) (PGD(2)), a major cyclooxygenase product in a variety of tissues, readily undergoes dehydration to yield the… (More)
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Prostaglandin (PG)D2, which has long been implicated in allergic diseases, is currently considered to elicit its biological… (More)
  • figure 1
  • figure 2
  • table I
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Prostaglandin D2 (PGD2) is released following exposure of asthmatics to allergen and acts via the adenylyl cyclase-coupled… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 6
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Allergic asthma is caused by the aberrant expansion in the lung of T helper cells that produce type 2 (TH2) cytokines and is… (More)
  • figure 2
  • figure 3
  • figure 4
  • figure 5
  • figure 1
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Cyclooxygenase (COX) has two isoforms. Generally, COX 1 is constitutively expressed in most tissues, where it maintains… (More)
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
1986
Highly Cited
1986
Among the many possible mediators of the early asthmatic response, prostaglandin D2, a bronchoconstrictor, is the principal… (More)
Is this relevant?
Highly Cited
1982
Highly Cited
1982
Anti-IgE-dependent activation of rat and human mast cells resulted in the preferential generation of the cyclooxygenase products… (More)
Is this relevant?