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Prostaglandin D2

Known as: D2, Prostaglandin, F2 alpha, 11-Dehydroprostaglandin, PGD2 
The principal cyclooxygenase metabolite of arachidonic acid. It is released upon activation of mast cells and is also synthesized by alveolar… Expand
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Background Activation of the group 2 innate lymphoid cell (ILC2) population leads to production of the classical type 2 cytokines… Expand
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Highly Cited
2006
Highly Cited
2006
Nicotinic acid (NA) is commonly used to treat dyslipidemia, but it elicits an adverse effect, termed flushing, which consists of… Expand
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Review
2002
Review
2002
Linoleic and alpha-linolenic acids, obtained from plant material in the diet are the precursors in tissues of two families with… Expand
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Highly Cited
2001
Highly Cited
2001
Prostaglandin (PG)D2, which has long been implicated in allergic diseases, is currently considered to elicit its biological… Expand
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Highly Cited
2001
Highly Cited
2001
Prostaglandin D2 (PGD2) is released following exposure of asthmatics to allergen and acts via the adenylyl cyclase-coupled… Expand
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Highly Cited
2000
Highly Cited
2000
Allergic asthma is caused by the aberrant expansion in the lung of T helper cells that produce type 2 (TH2) cytokines and is… Expand
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Highly Cited
1999
Highly Cited
1999
Cyclooxygenase (COX) has two isoforms. Generally, COX 1 is constitutively expressed in most tissues, where it maintains… Expand
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Highly Cited
1995
Highly Cited
1995
Human epidemiological and laboratory animal model studies have suggested that nonsteroidal antiinflammatory drugs reduce the risk… Expand
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Highly Cited
1986
Highly Cited
1986
Among the many possible mediators of the early asthmatic response, prostaglandin D2, a bronchoconstrictor, is the principal… Expand
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Highly Cited
1982
Highly Cited
1982
Anti-IgE-dependent activation of rat and human mast cells resulted in the preferential generation of the cyclooxygenase products… Expand
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