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dehydroxymethylepoxyquinomicin
Known as:
DHMEQ cpd
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Benzamides
Cyclohexanones
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Pleiotropic Potential of Dehydroxymethylepoxyquinomicin for NF-κB Suppression via Reactive Oxygen Species and Unfolded Protein Response
S. Nakajima
,
H. Kato
,
+4 authors
M. Kitamura
Journal of Immunology
2013
Corpus ID: 34590973
Dehydroxymethylepoxyquinomicin (DHMEQ) is a low-m.w. compound that strongly inhibits NF-κB. Previous reports showed that DHMEQ…
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2011
2011
Chemoenzymatic synthesis of (2R,3R,4R)-dehydroxymethylepoxyquinomicin (DHMEQ), a new activator of antioxidant transcription factor Nrf2.
Yukihiro Niitsu
,
Masatoshi Hakamata
,
+4 authors
K. Umezawa
Organic and biomolecular chemistry
2011
Corpus ID: 24896405
Dehydroxymethylepoxyquinomicin (DHMEQ, 1a) is a specific and potent inhibitor of NF-κB, and it is now being developed as an anti…
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2007
2007
Targeting NF-kappaB and induction of apoptosis by novel NF-kappaB inhibitor dehydroxymethylepoxyquinomicin (DHMEQ) in Burkitt lymphoma cells.
Noriko Kimura
,
Y. Miyakawa
,
Kanoko Kohmura
,
K. Umezawa
,
Y. Ikeda
,
M. Kizaki
Leukemia research : a Forum for Studies on…
2007
Corpus ID: 42897608
A new NF-kappaB inhibitor, dehydroxymethylepoxyquinomicin (DHMEQ), inhibited proliferation and induced apoptosis in human Burkitt…
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2006
2006
Control of Allograft Rejection by Applying a Novel Nuclear Factor-&kgr;B Inhibitor, Dehydroxymethylepoxyquinomicin
S. Ueki
,
K. Yamashita
,
+9 authors
S. Todo
Transplantation
2006
Corpus ID: 19957310
Background. Nuclear factor (NF)-&kgr;B plays a crucial role in lymphocyte activation, proliferation, and survival. We examined…
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Review
2006
Review
2006
Blocking NF-kappaB as a potential strategy to treat adult T-cell leukemia/lymphoma.
R. Horie
,
Toshiki Watanabe
,
K. Umezawa
Drug News and Perspectives
2006
Corpus ID: 42195460
Adult T-cell leukemia/lymphoma (ATL), a fatal T-cell leukemia/lymphoma resistant to chemotherapy, is caused by human T-cell…
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Highly Cited
2005
Highly Cited
2005
In vivo antitumor activity of the NF-kappaB inhibitor dehydroxymethylepoxyquinomicin in a mouse model of adult T-cell leukemia.
T. Ohsugi
,
R. Horie
,
+6 authors
T. Urano
Carcinogenesis
2005
Corpus ID: 41058364
Adult T-cell leukemia (ATL) is an aggressive neoplasm caused by human T-cell leukemia virus type I (HTLV-I). The nuclear…
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2005
2005
Inhibition of inflammatory cytokine secretion from mouse microglia cells by DHMEQ, an NF-kappaB inhibitor.
H. Takatsuna
,
S. Morita
,
T. Nagatsu
,
M. Sawada
,
K. Umezawa
Biomedicine & pharmacotherapy = Biomedecine…
2005
Corpus ID: 34532859
2005
2005
Dehydroxymethylepoxyquinomicin, a novel nuclear factor-kappaB inhibitor, induces apoptosis in multiple myeloma cells in an IkappaBalpha-independent manner.
Hiro Tatetsu
,
Y. Okuno
,
+7 authors
H. Hata
Molecular Cancer Therapeutics
2005
Corpus ID: 8802545
Nuclear factor-kappaB (NF-kappaB) is constitutively activated in multiple myeloma cells. Several proteasome inhibitors have been…
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2005
2005
Prevention of Cancer Cachexia by a Novel Nuclear Factor κB Inhibitor in Prostate Cancer
K. Kuroda
,
Y. Horiguchi
,
+6 authors
M. Murai
Clinical Cancer Research
2005
Corpus ID: 72969942
Purpose: To investigate the association between serum interleukin-6 (IL-6) and cachexia in patients with prostate cancer and the…
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2005
2005
Prevention of cancer cachexia by a novel nuclear factor {kappa}B inhibitor in prostate cancer.
K. Kuroda
,
Y. Horiguchi
,
+6 authors
M. Murai
Clinical Cancer Research
2005
Corpus ID: 20365301
PURPOSE To investigate the association between serum interleukin-6 (IL-6) and cachexia in patients with prostate cancer and the…
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