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dazmegrel

Known as: 1H-Indole-1-propanoic acid, 3-(1H-imidazol-1-ylmethyl)-2-methyl-, 3-(1H-imidazole-1-yl-methyl)-2-methyl-1H-indole-1-propanoic acid, 3-(Imidazol-1-ylmethyl)-2-methylindole-1-propionic Acid 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (4)

Enzyme InhibitorsImidazolesPlatelet Aggregation InhibitorsVasodilator Agents

Narrower (1)

UK 38,485

Papers overview

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1991
1991
Nephrotoxicity of cyclosporine: The role of platelet-activating factor and thromboxane
Cyclosporine (CsA), an immunosuppressive agent, is potentially nephrotoxic. We had previously observed that acute administration… 
1990
1990
Thromboxane A2 and Development of Genetic Hypertension in the Lyon Rat Strain
To determine whether the increased renal biosynthesis of thromboxane A2 observed in young genetically hypertensive rats of the… 
1988
1988
Stenosis and vascular damage as a cause of thrombosis in the dog femoral artery
SummaryWe describe here an experimental model of peripheral arterial thrombosis and the effect of several drugs which are known… 
1987
1987
Platelet changes after a saturated fat meal and their prevention by dazmegrel, a thromboxane synthetase inhibitor
A saturated fat meal was given to 10 normal males both before and after pretreatment with UK38,485, a thromboxane synthetase… 
Highly Cited
1986
Highly Cited
1986
Effects of the Thromboxane Synthetase Inhibitor, Dazmegrel (UK 38,485), on Pulmonary Gas Exchange and Hemodynamics in Neonatal Sepsis
ABSTRACT. Group B streptococcal (GBS) sepsis produces arterial hypoxemia in newborns. In piglets we previously found that… 
1986
1986
Synthesis of prostaglandin E2, thromboxane B2 and prostaglandin catabolism in gastritis and gastric ulcer.
Because endogenous prostaglandins may protect the gastric mucosa a study was conducted to determine factors influencing the… 
1986
1986
Effect of a thromboxane synthetase inhibitor on eicosanoid synthesis and glomerular injury during acute unilateral glomerulonephritis in the rat.
Eicosanoid synthesis was studied in a model of in situ glomerulonephritis (gn) in the rat. Unilateral gn was induced by perfusion… 
1986
1986
The platelet thromboxane inhibitor, dazmegrel, does not reduce monocrotaline-induced pulmonary hypertension.
Monocrotaline injures rat pulmonary endothelium, and pulmonary vascular remodeling, pulmonary hypertension, and right ventricular… 
1986
1986
A new combination therapy for selective and prolonged antiplatelet effect: results in the dog.
This study characterizes the effect of dazmegrel, a thromboxane synthetase inhibitor, on platelet function in the dog and… 
1985
1985
Opposing hemodynamic effects of substance P on pulmonary vasculature in rabbits.
Substance P is a peptide implicated in the control of a variety of physiological processes. Although substance P-containing…